Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 4/20 | 0.67 |
| ▸ | CYP27A1 | Q02318 | 2/20 | 0.66 |
| ▸ | CYP24A1 | Q07973 | 4/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | NPC1 | O15118 | 3/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | MIF | P14174 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.60 |
| ▸ | RELA | Q04206 | 1/20 | 0.60 |
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28096418 | 0.92 | MAOA (0.68) | CYP26A1CYP27A1CYP24A1SMN1; SMN2NPC1 | |
| SCHEMBL28095979 | 0.87 | MAPT (0.65) | SMN1; SMN2NPC1RAB9AHPGDLMNA | |
| SCHEMBL28833618 | 0.85 | BCHE (0.74) | CYP26A1CYP27A1CYP24A1SMN1; SMN2NPC1 | |
| SCHEMBL9619624 | 0.83 | ALDH1A1 (0.79) | CYP26A1CYP27A1CYP24A1SMN1; SMN2NPC1 | |
| SCHEMBL9619490 | 0.83 | NFE2L2 (0.71) | CYP26A1CYP27A1CYP24A1SMN1; SMN2NPC1 | |
| SCHEMBL229133 | 0.80 | CYP26A1 (0.76) | CYP26A1CYP27A1CYP24A1SMN1; SMN2NPC1 | |
| SCHEMBL16210588 | 0.80 | CYP26A1 (0.76) | CYP26A1CYP27A1CYP24A1SMN1; SMN2NPC1 | |
| SCHEMBL16210587 | 0.80 | CYP26A1 (0.76) | CYP26A1CYP27A1CYP24A1SMN1; SMN2NPC1 | |
| SCHEMBL229132 | 0.80 | CYP26A1 (0.76) | CYP26A1CYP27A1CYP24A1SMN1; SMN2NPC1 | |
| SCHEMBL12204782 | 0.79 | CYP26A1 (0.63) | CYP26A1CYP27A1CYP24A1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106278857-A | α, β unsaturated carbonyl tetralone derivative and application thereof | 武汉理工大学 | 2017-01-04 | — | — | CN | claimed |
| CN-106008324-A | Alpha,beta-unsaturated compounds and application thereof | 武汉理工大学 | 2016-10-12 | — | — | CN | claimed |
| CN-106278857-A | α, β unsaturated carbonyl tetralone derivative and application thereof | 武汉理工大学 | 2017-01-04 | — | — | CN | disclosed |
| CN-106008324-A | Alpha,beta-unsaturated compounds and application thereof | 武汉理工大学 | 2016-10-12 | — | — | CN | disclosed |