Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 6/20 | 0.47 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | FCER2 | P06734 | 3/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9109075 | 0.86 | HPGDS (0.56) | HPGDSCAPN1CTSBFCER2MMP1 | |
| SCHEMBL298697 | 0.85 | FPR2 (0.48) | HPGDSFCER2MMP1ACE | |
| SCHEMBL20397627 | 0.85 | FPR2 (0.48) | HPGDSFCER2MMP1 | |
| SCHEMBL26909780 | 0.85 | HPGDS (0.58) | HPGDSACE | |
| SCHEMBL18262574 | 0.85 | CA2 (0.49) | HPGDSCYP2C9CYP2C19PPARG | |
| SCHEMBL4348297 | 0.85 | HPGDS (0.58) | HPGDSACE | |
| SCHEMBL12495080 | 0.85 | FPR2 (0.48) | HPGDSFCER2MMP1 | |
| SCHEMBL18546526 | 0.85 | FPR2 (0.48) | HPGDSFCER2MMP1ACE | |
| SCHEMBL18262572 | 0.85 | CA2 (0.49) | HPGDSCYP2C9CYP2C19PPARG | |
| SCHEMBL18262496 | 0.81 | LDHA (0.57) | MMP1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105916499-A | 12-epi-pleuromutilins | 纳布里瓦治疗股份公司 | 2016-08-31 | — | — | CN | disclosed |