Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | PRKDC | P78527 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.44 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL310130 | 0.90 | LMNA (0.54) | LMNAALDH1A1TDP1MAPTKDM4E | |
| SCHEMBL8536622 | 0.90 | MERTK (0.51) | LMNAALDH1A1TDP1MAPTKDM4E | |
| SCHEMBL31188768 | 0.90 | LMNA (0.54) | LMNAALDH1A1TDP1MAPTKDM4E | |
| SCHEMBL30435204 | 0.90 | MERTK (0.51) | LMNAALDH1A1TDP1MAPTKDM4E | |
| SCHEMBL11661312 | 0.90 | ALDH1A1 (0.48) | LMNAALDH1A1TDP1MAPTKDM4E | |
| SCHEMBL29739541 | 0.87 | ALDH1A1 (0.49) | LMNAALDH1A1TDP1MAPTKDM4E | |
| SCHEMBL359390 | 0.87 | ALDH1A1 (0.49) | LMNAALDH1A1TDP1MAPTKDM4E | |
| Methyl Alcohol SCHEMBL28097248 | 0.87 | LMNA (0.55) | LMNAALDH1A1TDP1MAPTKDM4E | |
| SCHEMBL11416083 | 0.87 | ALDH1A1 (0.46) | LMNAALDH1A1TDP1MAPTKDM4E | |
| SCHEMBL3122999 | 0.87 | RAB9A (0.50) | LMNAALDH1A1TDP1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170369486-A1 | GEMINAL SUBSTITUTED QUINUCLIDINE AMIDE COMPOUNDS AS AGONISTS OF ALPHA-7 NICOTONIC ACETYLCHOLINE RECEPTORS | AXOVANT SCIENCES GMBH (CH) | 2017-12-28 | — | — | US | disclosed |
| US-4532350-A | Process for the selective preparation of meta-chloroanilines | RHONE-POULENC AGROCHIMIE (FR) | 1985-07-30 | — | — | US | disclosed |
| EP-0045709-B1 | PROCESS FOR THE PREPARATION OF META-CHLORINATED ANILINES | RHONE-POULENC AGROCHIMIE (FR) | 1984-10-03 | — | — | EP | disclosed |
| EP-0045710-B1 | PROCESS FOR THE SELECTIVE PREPARATION OF META-CHLORINATED ANILINES | RHONE-POULENC AGROCHIMIE (FR) | 1984-07-04 | — | — | EP | disclosed |
| US-4418213-A | HYDRODEHALOGENATION LEWIS ACID AND NOBLE METAL CATALYSTS | RHONE-POULENC AGROCHIMIE (FR) | 1983-11-29 | — | — | US | disclosed |
| US-4351959-A | Process for preparation of anilines substituted by chlorine in the meta-position | RHONE-POULENC AGROCHIMIE (FR) | 1982-09-28 | — | — | US | disclosed |
| US-4340759-A | Process for the preparation of anilines substituted by chlorine in the meta-position | RHONE-POULENC AGROCHIMIE (FR) | 1982-07-20 | — | — | US | disclosed |
| EP-0015220-B1 | PROCESS FOR THE PREPARATION OF META-CHLORO ANILINES | RHONE-POULENC AGROCHIMIE (FR) | 1982-05-12 | — | — | EP | disclosed |
| US-4324914-A | Process for preparation of anilines substituted by chlorine in the meta-position | RHONE-POULENC AGROCHIMIE (FR) | 1982-04-13 | — | — | US | disclosed |
| EP-0045709-A1 | Process for the preparation of meta-chlorinated anilines | RHONE-POULENC AGROCHIMIE (FR) | 1982-02-10 | — | — | EP | disclosed |
| EP-0045710-A1 | Process for the selective preparation of meta-chlorinated anilines | RHONE-POULENC AGROCHIMIE (FR) | 1982-02-10 | — | — | EP | disclosed |
| EP-0015219-B1 | PROCESS FOR THE PREPARATION OF META-CHLORO ANILINES | RHONE-POULENC AGROCHIMIE (FR) | 1981-10-28 | — | — | EP | disclosed |
| EP-0015220-A1 | Process for the preparation of meta-chloro anilines | RHONE-POULENC AGROCHIMIE (FR) | 1980-09-03 | — | — | EP | disclosed |
| EP-0015219-A1 | Process for the preparation of meta-chloro anilines | RHONE-POULENC AGROCHIMIE (FR) | 1980-09-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170369486-A1 | GEMINAL SUBSTITUTED QUINUCLIDINE AMIDE COMPOUNDS AS AGONISTS OF ALPHA-7 NICOTONIC ACETYLCHOLINE RECEPTORS | CHRNA7, CHRNA6, CHRNA5 | LMNA 2908/4885ALDH1A1 2708/4885TDP1 1948/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.