SCHEMBL310130

SCHEMBL310130

COc1cc([N+](=O)[O-])c(OC)cc1Cl

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.54
ALDH1A1 P00352 4/20 0.51
MAPT P10636 4/20 0.51
CYP3A4 P08684 2/20 0.51
KDM4E B2RXH2 1/20 0.51
ALOX15 P16050 1/20 0.51
PRKDC P78527 1/20 0.51
HSD17B10 Q99714 1/20 0.51
TDP1 Q9NUW8 3/20 0.48
HPGD P15428 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
NPC1 O15118 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
RAB9A P51151 1/20 0.46
HTT P42858 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.43
S1PR4 O95977 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31188768 1.00 LMNA (0.54) LMNAALDH1A1MAPTCYP3A4KDM4E
Methyl Alcohol SCHEMBL28097248 0.96 LMNA (0.55) LMNAALDH1A1MAPTCYP3A4KDM4E
SCHEMBL11661312 0.92 ALDH1A1 (0.48) LMNAALDH1A1MAPTCYP3A4KDM4E
SCHEMBL10983166 0.90 LMNA (0.51) LMNAALDH1A1MAPTCYP3A4KDM4E
SCHEMBL30435204 0.89 MERTK (0.51) LMNAALDH1A1MAPTCYP3A4KDM4E
SCHEMBL8536622 0.89 MERTK (0.51) LMNAALDH1A1MAPTCYP3A4KDM4E
SCHEMBL10814747 0.89 ALDH1A1 (0.51) LMNAALDH1A1MAPTCYP3A4KDM4E
SCHEMBL2874199 0.89 LMNA (0.50) LMNAALDH1A1MAPTCYP3A4KDM4E
SCHEMBL10778338 0.88 ALDH1A1 (0.62) LMNAALDH1A1MAPTCYP3A4KDM4E
SCHEMBL3103536 0.86 LMNA (0.59) LMNAALDH1A1MAPTCYP3A4KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036510-A Method for continuously synthesizing 2, 5-dimethoxy-4-nitrochlorobenzene 福建砺善和光工程技术研究有限公司 2026-05-15 CN claimed
CN-119059913-A Method for preparing 4-chloro-2, 5-dimethoxy nitrobenzene by one-pot chlorination nitration reaction 南京工业大学 2024-12-03 CN claimed
CN-221999816-U 4-Chloro-2, 5-dimethoxy nitrobenzene feeding device 大名县名鼎化工有限责任公司 2024-11-15 CN claimed
CN-218664348-U 4-chlorine-2,5-dimethoxy nitrobenzene automatic discharging device 大名县名鼎化工有限责任公司 2023-03-21 CN claimed
CN-110698353-B Preparation method of 4-chloro-2,5-dimethoxyaniline 河北彩客新材料科技股份有限公司 2022-11-22 CN claimed
CN-115260044-A Preparation process of high-purity 2,5-dimethoxy-4-chloro-diethylaniline 盐城华钛化学有限公司 2022-11-01 CN claimed
CN-212942945-U 4-chloro-2, 5-dimethoxyl nitrobenzene synthesis reaction tank 大名县名鼎化工有限责任公司 2021-04-13 CN claimed
CN-212262578-U Integrated machine for filtering, washing and dehydrating 4-chloro-2, 5-dimethoxy nitrobenzene 大名县名鼎化工有限责任公司 2021-01-01 CN claimed
CN-111960947-A Method for synthesizing 4-chloro-2, 5-dimethoxy nitrobenzene by using microreactor 百合花集团股份有限公司 2020-11-20 CN claimed
CN-110698353-A Preparation method of 4-chloro-2, 5-dimethoxyaniline 彩客化学(沧州)有限公司 2020-01-17 CN claimed
CN-103265441-B Preparation method of 2,5-dimethoxyl-4-chloroaniline XIANGSHUI HENRYDA TECH CHEMICAL CO LTD 2014-06-11 CN claimed
CN-102343264-B Preparation method of 2,5-dimethoxy-4-chloronitrobenzene hydrogenation catalyst HEBEI HUA CHEM DYE CHEMICAL CO LTD 2013-09-18 CN claimed
CN-103265441-A Preparation method of 2,5-dimethoxyl-4-chloroaniline XIANGSHUI HENRYDA TECH CHEMICAL CO LTD 2013-08-28 CN claimed
CN-102344382-A Method for preparing 2,5-dimethoxy-4-chloroaniline by hydrogenation reduction HEBEI HUA CHEM DYE CHEMICAL CO LTD 2012-02-08 CN claimed
CN-102344380-A Method for preparing 2,5-dimethoxy-4-chloroaniline by using liquid-phase catalytic hydrogenation method JIANGSU LIDANING CHEMICAL CO LTD 2012-02-08 CN claimed
CN-102343264-A Preparation method of 2,5-dimethoxy-4-chloronitrobenzene hydrogenation catalyst HEBEI HUA CHEM DYE CHEMICAL CO LTD 2012-02-08 CN claimed
EP-0347796-B1 PREPARATION PROCESS OF 4-CHLORO-2,5-DIMETHOXY-ANILINE HOECHST AKTIENGESELLSCHAFT (DE) 1993-08-04 EP claimed
US-5041671-A Process for the preparation 4-chloro-2,5-dimethoxy-aniline HOECHST AKTIENGESELLSCHAFT (DE) 1991-08-20 US claimed
EP-0347796-A2 Preparation process of 4-chloro-2,5-dimethoxy-aniline HOECHST AKTIENGESELLSCHAFT (DE) 1989-12-27 EP claimed
US-4082803-A PROCESS FOR PREPARING 4-CHLORO-2,5-DIMETHOXY ANILINE HOECHST AKTIENGESELLSCHAFT (DT) 1978-04-04 US claimed