Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 2/20 | 0.32 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7068809 | 0.82 | GFER (0.45) | ALDH1A1 | |
| SCHEMBL3819186 | 0.81 | IDO1 (0.41) | TAAR1HTR2AIDO1ALDH1A1KDM4E | |
| SCHEMBL11948259 | 0.80 | TAAR1 (0.41) | TAAR1HTR2APOLBCTDSP1 | |
| SCHEMBL7795405 | 0.76 | TAAR1 (0.35) | TAAR1HTR2A | |
| SCHEMBL9813439 | 0.76 | TAAR1 (0.35) | TAAR1HTR2AIDO1ALDH1A1KDM4E | |
| SCHEMBL2600041 | 0.74 | TAAR1 (0.50) | TAAR1HTR2AIDO1POLBCTDSP1 | |
| SCHEMBL6212376 | 0.73 | WNT3A (0.34) | — | |
| SCHEMBL7005101 | 0.73 | TAAR1 (0.45) | TAAR1HTR2AIDO1POLBCTDSP1 | |
| SCHEMBL6212657 | 0.71 | EP300 (0.35) | — | |
| SCHEMBL2809807 | 0.71 | TAAR1 (0.40) | TAAR1HTR2AIDO1POLBCTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240612-A1 | Prenylated Bisphosphonates as Anti-tuberculosis Agents | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240612-A1 | Prenylated Bisphosphonates as Anti-tuberculosis Agents | GGPS1, FDPS, DCTPP1 | TAAR1 4284/4885HTR2A 4880/4885IDO1 4163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.