Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.40 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ESRRG | P62508 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GRK6 | P43250 | 1/20 | 0.34 |
| ▸ | GLS | O94925 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2809804 | 0.82 | TAAR1 (0.40) | ALDH1A1 | |
| SCHEMBL3847127 | 0.80 | MAOB (0.47) | CYP19A1MAOBMAOACYP3A4RAB9A | |
| SCHEMBL13363663 | 0.80 | GFER (0.46) | GFERCYP19A1MAOBMAOAALDH1A1 | |
| SCHEMBL7337658 | 0.76 | MAOB (0.35) | GFERCYP19A1MAOBMAOAALDH1A1 | |
| SCHEMBL532667 | 0.76 | MAOB (0.46) | GFERCYP19A1MAOBMAOANPC1 | |
| SCHEMBL24838443 | 0.75 | GFER (0.54) | GFERCYP19A1MAOBMAOAALDH1A1 | |
| SCHEMBL7388083 | 0.74 | GFER (0.59) | GFERCYP19A1MAOBMAOAALDH1A1 | |
| SCHEMBL6212376 | 0.73 | WNT3A (0.34) | — | |
| SCHEMBL11131886 | 0.72 | GFER (0.56) | GFERCYP19A1MAOBMAOAALDH1A1 | |
| SCHEMBL3843060 | 0.72 | SIGMAR1 (0.33) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030187054-A1 | Preparations for chondrogenesis | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-10-02 | — | — | US | disclosed |
| EP-1266664-A1 | PREPARATIONS FOR CHONDROGENESIS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-12-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187054-A1 | Preparations for chondrogenesis | COL2A1, BMP2, COL1A1 | GFER 4556/4885CYP19A1 1147/4885MAOB 3469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.