Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 2/20 | 0.40 |
| ▸ | RXRB | P28702 | 2/20 | 0.40 |
| ▸ | RXRG | P48443 | 2/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9242571 | 0.81 | HSD11B1 (0.53) | HSD11B1RXRARXRBRXRGTRPA1 | |
| SCHEMBL4654446 | 0.80 | RXRA (0.47) | HSD11B1RXRARXRBRXRGTRPA1 | |
| SCHEMBL6371363 | 0.77 | TDP1 (0.47) | HSD11B1RXRARXRBRXRGGAA | |
| SCHEMBL2090915 | 0.74 | HSD11B1 (0.40) | HSD11B1RXRARXRBRXRGTRPA1 | |
| SCHEMBL2090917 | 0.74 | HSD11B1 (0.40) | HSD11B1RXRARXRBRXRGTRPA1 | |
| SCHEMBL16579384 | 0.74 | HSD11B1 (0.44) | HSD11B1RXRARXRBRXRGTRPA1 | |
| SCHEMBL7701143 | 0.73 | ALDH1A1 (0.50) | HSD11B1TRPA1ALDH1A1L3MBTL1SCN9A | |
| SCHEMBL30707956 | 0.72 | RXRA (0.47) | HSD11B1RXRARXRBRXRGGAA | |
| SCHEMBL17420774 | 0.72 | RXRA (0.47) | HSD11B1RXRARXRBRXRGGAA | |
| SCHEMBL27660142 | 0.72 | HSD11B1 (0.62) | HSD11B1TRPA1TRPM8TRPV1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105873908-A | Novel compounds for combating arthropods | 拜耳作物科学股份公司 | 2016-08-17 | — | — | CN | disclosed |