Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2090917 | 1.00 | HSD11B1 (0.40) | HSD11B1GAARXRARXRBRXRG | |
| SCHEMBL2099505 | 0.82 | — | — | |
| SCHEMBL2099503 | 0.82 | — | — | |
| SCHEMBL4654446 | 0.82 | RXRA (0.47) | HSD11B1GAARXRARXRBRXRG | |
| SCHEMBL9242571 | 0.78 | HSD11B1 (0.53) | HSD11B1GAARXRARXRBRXRG | |
| SCHEMBL7701143 | 0.75 | ALDH1A1 (0.50) | HSD11B1ALDH1A1L3MBTL1SCN9APOLB | |
| SCHEMBL28098554 | 0.74 | HSD11B1 (0.42) | HSD11B1GAARXRARXRBRXRG | |
| SCHEMBL6371363 | 0.74 | TDP1 (0.47) | HSD11B1GAARXRARXRBRXRG | |
| SCHEMBL30707956 | 0.74 | RXRA (0.47) | HSD11B1GAARXRARXRBRXRG | |
| SCHEMBL17420774 | 0.74 | RXRA (0.47) | HSD11B1GAARXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070299100-A1 | Analgesic | TORAY INDUSTRIES, INC. (JP) | 2007-12-27 | — | — | US | claimed |
| EP-1820505-A1 | ANALGESIC | TORAY INDUSTRIES, INC. (JP) | 2007-08-22 | — | — | EP | claimed |
| EP-2168579-B1 | ORAL PREPARATION COMPRISING SPECIFIC ORGANIC ACID, AND METHOD FOR IMPROVEMENT IN DISSOLUTION PROPERTY AND CHEMICAL STABILITY OF ORAL PREPARATION | TORAY INDUSTRIES (JP) | 2017-10-11 | — | — | EP | disclosed |
| US-9084817-B2 | Oral preparation comprising specific organic acid, and method for improvement in elution property and chemical stability of oral preparation | TORAY INDUSTRIES, INC. (JP) | 2015-07-21 | — | — | US | disclosed |
| EP-2156838-B1 | METHOD FOR PRODUCING PHARMACEUTICAL TABLET | TORAY INDUSTRIES (JP) | 2015-01-21 | — | — | EP | disclosed |
| US-8927011-B2 | Method for producing pharmaceutical tablet | TORAY INDUSTRIES, INC. (JP) | 2015-01-06 | — | — | US | disclosed |
| EP-1555266-B1 | REMEDIES OR PREVENTIVES FOR URINARY INCONTINENCE AND MORPHINAN DERIVATIVES HAVING NITROGEN-CONTAINING HETEROCYCLIC GROUP | TORAY INDUSTRIES (JP) | 2014-05-21 | — | — | EP | disclosed |
| US-8470845-B2 | Analgesic and methods of treating pain | TORAY INDUSTRIES, INC. (JP) | 2013-06-25 | — | — | US | disclosed |
| US-8163753-B2 | 2-(4-(4-(4-chlorophenyl)oxazol-2-yl)phenoxymethyl)-2-methyl-6-nitro-2,3-dihydroimidazo[2,1-b]oxazole; bactericide; excellent bactericidal action against Mycobacterium tuberculosis, multi-drug-resistant Mycobacterium tuberculosis, and atypical acid-fast bacteria | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2012-04-24 | — | — | US | disclosed |
| US-20100215750-A1 | ORAL PREPARATION COMPRISING SPECIFIC ORGANIC ACID, AND METHOD FOR IMPROVEMENT IN ELUTION PROPERTY AND CHEMICAL STABILITY OF ORAL PREPARATION | TORAY INDUSTRIES, INC. (JP) | 2010-08-26 | — | — | US | disclosed |
| US-20100151016-A1 | METHOD FOR PRODUCING PHARMACEUTICAL TABLET | TORAY INDUSTRIES, INC. (JP) | 2010-06-17 | — | — | US | disclosed |
| US-20080119478-A1 | 2,3-Dihydro-6-Nitroimidazo (2,1-b) Oxazole Compounds for the Treatment of Tuberculosis | OTSUKA PHAMACEUTICAL CO., LTD. (JP) | 2008-05-22 | — | — | US | disclosed |
| US-7320984-B2 | Remedies or preventives for urinary frequency or urinary incontinence and morphinan derivatives having nitrogen-containing heterocyclic group | TORAY INDUSTRIES, INC. (JP) | 2008-01-22 | — | — | US | disclosed |
| US-20070299100-A1 | Analgesic | TORAY INDUSTRIES, INC. (JP) | 2007-12-27 | — | — | US | disclosed |
| EP-1820505-A1 | ANALGESIC | TORAY INDUSTRIES, INC. (JP) | 2007-08-22 | — | — | EP | disclosed |
| EP-1736157-A1 | ANTI-ITCHING AGENT | TORAY INDUSTRIES, INC. (JP) | 2006-12-27 | — | — | EP | disclosed |
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| US-20060040970-A1 | Remedies or preventives for urinary frequency or urinary incontinence and morphinan derivatives having nitrogen-containing heterocyclic group | TORAY INDUSTRIES, INC. (JP) | 2006-02-23 | — | — | US | disclosed |
| EP-1555266-A1 | REMEDIES OR PREVENTIVES FOR URINARY FREQUENCY OR URINARY INCONTINENCE AND MORPHINAN DERIVATIVES HAVING NITROGEN-CONTAINING HETEROCYCLIC GROUP | TORAY INDUSTRIES, INC. (JP) | 2005-07-20 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070299100-A1 | Analgesic | OPRK1, OPRL1, OPRM1 | HSD11B1 1972/4885GAA 2620/4885RXRA 1373/4885 |
| US-20080119478-A1 | 2,3-Dihydro-6-Nitroimidazo (2,1-b) Oxazole Compounds for the Treatment of Tuberculosis | NR2C2, NR0B2, NR4A2 | HSD11B1 773/4885GAA 3982/4885RXRA 179/4885 |
| US-20100151016-A1 | METHOD FOR PRODUCING PHARMACEUTICAL TABLET | FASN, SORD, SDHA | HSD11B1 330/4885GAA 359/4885RXRA 2731/4885 |
| US-20100215750-A1 | ORAL PREPARATION COMPRISING SPECIFIC ORGANIC ACID, AND METHOD FOR IMPROVEMENT IN ELUTION PROPERTY AND CHEMICAL STABILITY OF ORAL PREPARATION | SORD, OSTC, OAT | HSD11B1 375/4885GAA 546/4885RXRA 924/4885 |
| US-20060040970-A1 | Remedies or preventives for urinary frequency or urinary incontinence and morphinan derivatives having nitrogen-containing heterocyclic group | MYH10, H1-10, MB | HSD11B1 1969/4885GAA 2746/4885RXRA 807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.