Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.34 |
| ▸ | F9 | P00740 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 4/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28295766 | 0.77 | WNT3A (0.42) | CSNK1DCSNK1EMAPK14HCRTR1HCRTR2 | |
| SCHEMBL28185372 | 0.77 | ORAI1 (0.38) | CSNK1DCSNK1EMAPK14ORAI1HCRTR1 | |
| SCHEMBL28224493 | 0.74 | GABRA1 (0.40) | CSNK1DCSNK1EMAPK14HCRTR1HCRTR2 | |
| SCHEMBL28296425 | 0.74 | HCRTR1 (0.38) | CSNK1DCSNK1EMAPK14HCRTR1HCRTR2 | |
| SCHEMBL20403686 | 0.69 | STING1 (0.42) | HCRTR1HCRTR2BRAFCYP11B2STING1 | |
| SCHEMBL18248463 | 0.68 | CYP11B2 (0.38) | HDAC4KAT6ACYP11B2ADORA2AADORA2B | |
| SCHEMBL28284386 | 0.66 | MAP4K1 (0.38) | HCRTR1HCRTR2KAT6ACYP11B2 | |
| SCHEMBL22635953 | 0.64 | CYP11B2 (0.50) | CSNK1DCSNK1EMAPK14CYP11B2ADORA2A | |
| SCHEMBL17432889 | 0.63 | WNT3A (0.39) | HCRTR1HCRTR2HDAC4KAT6ACYP11B2 | |
| SCHEMBL13911005 | 0.62 | LOXL2 (0.40) | BRAFHDAC4CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105263921-B | Terazololine-one compound and its application | 住友化学株式会社 | 2017-07-21 | — | — | CN | disclosed |
| CN-104822666-B | Terazololine-one compound and application thereof | 住友化学株式会社 | 2016-09-21 | — | — | CN | disclosed |