Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.33 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.33 |
| ▸ | FEN1 | P39748 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28224493 | 0.76 | GABRA1 (0.40) | HCRTR1HCRTR2CSNK1DCSNK1EMAPK14 | |
| SCHEMBL28295766 | 0.76 | WNT3A (0.42) | HCRTR1HCRTR2CSNK1DCSNK1EMAPK14 | |
| SCHEMBL28185372 | 0.76 | ORAI1 (0.38) | HCRTR1HCRTR2CSNK1DCSNK1EMAPK14 | |
| SCHEMBL28098586 | 0.74 | CSNK1D (0.36) | HCRTR1HCRTR2ADORA2AADORA2BADORA1 | |
| SCHEMBL18378750 | 0.73 | TRPA1 (0.39) | HCRTR1HCRTR2NPC1RAB9AALDH1A1 | |
| SCHEMBL28284386 | 0.73 | MAP4K1 (0.38) | HCRTR1HCRTR2GABRA1GABRG2GABRB3 | |
| SCHEMBL5318296 | 0.72 | TRPA1 (0.41) | MAPK14NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL27821400 | 0.72 | HDAC4 (0.44) | HCRTR1HCRTR2CSNK1DCSNK1EMAPK14 | |
| SCHEMBL17035493 | 0.70 | ACHE (0.46) | ACHEGAAMGAMSIMGAM2 | |
| SCHEMBL14886180 | 0.69 | ACHE (0.44) | HCRTR1HCRTR2ACHEGAAGABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109843065-A | Active agent combinations comprising the 5- imdazole derivatives replaced | 拜耳作物科学股份公司 | 2019-06-04 | — | — | CN | claimed |