SCHEMBL28099680

SCHEMBL28099680

CS(=O)(=O)c1cc(Cl)ccc1C(F)(F)F

nearest known ligand 0.51

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CCR2 P41597 8/20 0.51
KIF11 P52732 1/20 0.42
SLC22A12 Q96S37 2/20 0.42
MCL1 Q07820 1/20 0.41
PKM P14618 1/20 0.40
RAB9A P51151 1/20 0.40
HTT P42858 1/20 0.40
P2RX1 P51575 1/20 0.40
DDR1 Q08345 1/20 0.39
CNR2 P34972 1/20 0.39
NOTUM Q6P988 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18469744 0.85 CCR2 (0.44) CCR2MCL1
SCHEMBL3410514 0.83 TRPV4 (0.47) CCR2SLC22A12MCL1PKMRAB9A
SCHEMBL16019362 0.81 CCR2 (0.41) CCR2MCL1RAB9A
SCHEMBL5832588 0.81 P2RX1 (0.43) CCR2SLC22A12MCL1PKMRAB9A
SCHEMBL23841300 0.79 CES2 (0.47) KIF11DDR1
SCHEMBL29217890 0.78 KIF11 (0.42) CCR2KIF11SLC22A12NOTUM
SCHEMBL6682359 0.77 SLC22A12 (0.45) CCR2SLC22A12MCL1P2RX1CNR2
SCHEMBL27620005 0.77 CCR2 (0.41) CCR2SLC22A12MCL1PKMRAB9A
SCHEMBL1492595 0.77 EPHX2 (0.39) CCR2HTTDDR1
SCHEMBL4012968 0.76 CCR2 (0.56) CCR2CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119654326-A Novel heterocyclic compounds 豪夫迈·罗氏有限公司 2025-03-18 CN disclosed
CN-105985246-A Diphenyl-ether compound with weeding or insecticidal or bactericidal activity 湖南化工研究院有限公司 2016-10-05 CN disclosed