Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2332472 | 0.76 | LMNA (0.39) | HTR2ALMNACYP2A6MEN1KMT2A | |
| SCHEMBL314557 | 0.74 | HTR2A (0.41) | HTR2ALMNAMEN1KMT2ARELA | |
| SCHEMBL7572963 | 0.73 | HTR2A (0.48) | HTR2ASLC6A2TAAR1MAOASLC6A4 | |
| SCHEMBL10497155 | 0.73 | LMNA (0.46) | HTR2ALMNAMEN1KMT2ARELA | |
| SCHEMBL8007285 | 0.72 | HTR2A (0.41) | HTR2AMAOALMNACYP2A6EPHX1 | |
| SCHEMBL14910835 | 0.71 | LMNA (0.45) | HTR2ATAAR1LMNAMEN1KMT2A | |
| SCHEMBL28771427 | 0.70 | MEN1 (0.48) | MAOAMEN1KMT2A | |
| Styrene SCHEMBL3014787 | 0.70 | ALDH1A1 (0.58) | HTR2ASLC6A2TAAR1MAOASLC6A4 | |
| SCHEMBL27839122 | 0.70 | HTR2A (0.46) | HTR2ASLC6A2TAAR1MAOASLC6A4 | |
| SCHEMBL27293430 | 0.70 | LMNA (0.34) | HTR2ASIGMAR1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103826661-B | Novel binding agent-drug conjugates (ADCs) and uses thereof | 西雅图基因公司 | 2019-03-05 | — | — | CN | disclosed |
| CN-106117312-A | New bonding agent drug conjugate (ADC) and application thereof | 西雅图基因公司 | 2016-11-16 | — | — | CN | disclosed |