Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SRC | P12931 | 9/20 | 0.48 |
| ▸ | HCK | P08631 | 1/20 | 0.48 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | FYN | P06241 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2788332 | 0.83 | PIK3CA (0.55) | MAPTALDH1A1KDM4ELMNASRC | |
| SCHEMBL2785338 | 0.81 | SRC (0.56) | SRCHCKPIM1MEN1KMT2A | |
| SCHEMBL2195032 | 0.75 | HTR2C (0.57) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL2810178 | 0.75 | GAA (0.56) | MAPTSRCMEN1KMT2AGAA | |
| SCHEMBL2861478 | 0.74 | MAPT (0.56) | MAPTALDH1A1KDM4ELMNATP53 | |
| SCHEMBL30095837 | 0.72 | PDE2A (0.39) | — | |
| SCHEMBL2804826 | 0.72 | PDE2A (0.39) | — | |
| SCHEMBL13943683 | 0.72 | HTR2C (0.76) | MAPTALDH1A1KDM4ELMNATP53 | |
| SCHEMBL2804593 | 0.71 | ALDH1A1 (0.54) | MAPTALDH1A1KDM4ELMNASRC | |
| SCHEMBL17726004 | 0.71 | FYN (0.71) | SRCHCKPIM1FYNABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118367-A2 | ANTIVIRAL PYRIMIDINES | PROGENICS PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |