Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.51 |
| ▸ | CFTR | P13569 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.50 |
| ▸ | HPGD | P15428 | 7/20 | 0.50 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | FADS1 | O60427 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27484400 | 0.80 | TRIM24 (0.38) | ALDH1A1HSD17B10KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL1558090 | 0.79 | ALDH1A1 (0.59) | ALDH1A1HSD17B10CFTRKDM4EHPGD | |
| SCHEMBL4315070 | 0.77 | ALDH1A1 (0.61) | ALDH1A1HSD17B10SMN1; SMN2MAPK1POLB | |
| SCHEMBL1534012 | 0.77 | ALDH1A1 (0.66) | ALDH1A1HSD17B10CFTRKDM4EHPGD | |
| SCHEMBL692347 | 0.77 | ALDH1A1 (0.66) | ALDH1A1HSD17B10CFTRKDM4EHPGD | |
| SCHEMBL28221971 | 0.76 | CES2 (0.47) | ALDH1A1KDM4EHPGDSMN1; SMN2TP53 | |
| SCHEMBL27584095 | 0.76 | HTT (0.59) | ALDH1A1KDM4EHPGDSMN1; SMN2POLB | |
| SCHEMBL1202541 | 0.75 | ALDH1A1 (0.64) | ALDH1A1HSD17B10CFTRKDM4EHPGD | |
| SCHEMBL8745364 | 0.74 | ALDH1A1 (0.60) | ALDH1A1HSD17B10CFTRKDM4EHPGD | |
| SCHEMBL28828371 | 0.74 | MEN1 (0.47) | ALDH1A1HSD17B10KDM4ESMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101400699-A | Human glucagon-like-peptide-1 modulators and their use in the treatment of diabetes and related conditions | BRISTOL MYERS SQUIBB CO (US) | 2009-04-01 | — | — | CN | claimed |
| CN-102844327-B | Template-fixed peptidomimetics with CXCR7 modulatory activity | 波利弗尔股份公司 | 2016-10-26 | — | — | CN | disclosed |