Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.66 |
| ▸ | CFTR | P13569 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.54 |
| ▸ | HPGD | P15428 | 7/20 | 0.54 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | FADS1 | O60427 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25237530 | 0.88 | NPC1 (0.58) | ALDH1A1HSD17B10CFTRKDM4EHPGD | |
| SCHEMBL17545031 | 0.80 | LMNA (0.62) | ALDH1A1HSD17B10KDM4EHPGDRAB9A | |
| SCHEMBL7126868 | 0.80 | HPGD (0.56) | ALDH1A1KDM4EHPGDRAB9ANPC1 | |
| SCHEMBL6671452 | 0.79 | ALDH1A1 (0.55) | ALDH1A1HSD17B10CFTRKDM4EHPGD | |
| SCHEMBL1558090 | 0.79 | ALDH1A1 (0.59) | ALDH1A1HSD17B10CFTRKDM4EHPGD | |
| SCHEMBL375579 | 0.79 | ALDH1A1 (0.59) | ALDH1A1HSD17B10CFTRKDM4EHPGD | |
| Methyl Anthranilate SCHEMBL29564148 | 0.79 | ALDH1A1 (1.00) | ALDH1A1HSD17B10CFTRKDM4EHPGD | |
| Methyl Anthranilate SCHEMBL901249 | 0.79 | ALDH1A1 (1.00) | ALDH1A1HSD17B10CFTRKDM4EHPGD | |
| Methyl Anthranilate SCHEMBL57713 | 0.79 | ALDH1A1 (1.00) | ALDH1A1HSD17B10CFTRKDM4EHPGD | |
| Methyl Anthranilate SCHEMBL29444250 | 0.79 | ALDH1A1 (1.00) | ALDH1A1HSD17B10CFTRKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119874631-A | Synthesis method of 1,2, 3-benzotriazine-4-ketone | 河北凯诺中星科技有限公司 | 2025-04-25 | — | — | CN | claimed |
| CN-118772064-A | Pyrimidine compound containing nitrogen methoxy benzamide and preparation method and application thereof | 贵州大学 | 2024-10-15 | — | — | CN | claimed |
| US-12391664-B2 | GluN2C/D subunit selective antagonists of the N-methyl-D-aspartate receptor | EMORY UNIVERSITY (US) | 2025-08-19 | — | — | US | disclosed |
| CN-119874631-A | Synthesis method of 1,2, 3-benzotriazine-4-ketone | 河北凯诺中星科技有限公司 | 2025-04-25 | — | — | CN | disclosed |
| CN-119874631-A | Synthesis method of 1,2, 3-benzotriazine-4-ketone | 河北凯诺中星科技有限公司 | 2025-04-25 | — | — | CN | disclosed |
| CN-118772064-A | Pyrimidine compound containing nitrogen methoxy benzamide and preparation method and application thereof | 贵州大学 | 2024-10-15 | — | — | CN | disclosed |
| US-20240294493-A1 | GluN2C/D Subunit Selective Antagonists of the N-Methyl-D-Aspartate Receptor | UNIV EMORY (US) | 2024-09-05 | — | — | US | disclosed |
| US-11981652-B2 | GluN2C/D subunit selective antagonists of the N-methyl-D-aspartate receptor | EMORY UNIVERSITY (US) | 2024-05-14 | — | — | US | disclosed |
| US-11981665-B2 | Substituted pyrimidines, pharmaceutical compositions and therapeutic methods thereof | CHEN ZHIHONG (US) | 2024-05-14 | — | — | US | disclosed |
| CN-111683662-B | Substituted pyrimidine compounds, pharmaceutical compositions and methods of treatment | 陈志宏 | 2024-04-02 | — | — | CN | disclosed |
| CN-117043151-A | Pyrimidine or pyridine derivative and medical application thereof | 希格生科（深圳）有限公司 | 2023-11-10 | — | — | CN | disclosed |
| US-20100113475-A1 | PYRAZOLYLAMINOPYRIDINES AS INHIBITORS OF FAK | GLAXOSMITHKLINE LLC | 2010-05-06 | — | — | US | disclosed |
| US-20100113475-A1 | PYRAZOLYLAMINOPYRIDINES AS INHIBITORS OF FAK | GLAXOSMITHKLINE LLC | 2010-05-06 | — | — | US | disclosed |
| WO-2009153589-A1 | PYRIDINE COMPOUNDS | ASTRAZENECA AB (SE) | 2009-12-23 | — | — | WO | disclosed |
| WO-2009105498-A1 | ANILINOPYRIDINES AS INHIBITORS OF FAK | SMITHKLINE BEECHAM CORPORATION (US) | 2009-08-27 | — | — | WO | disclosed |
| WO-2009105498-A1 | ANILINOPYRIDINES AS INHIBITORS OF FAK | SMITHKLINE BEECHAM CORPORATION (US) | 2009-08-27 | — | — | WO | disclosed |
| EP-0979227-A1 | 4,1-BENZOXAZEPINES, THEIR ANALOGUES, AND THEIR USE AS SOMATOSTATIN AGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2000-02-16 | — | — | EP | disclosed |
| WO-1998047882-A1 | 4,1-BENZOXAZEPINES, THEIR ANALOGUES, AND THEIR USE AS SOMATOSTATIN AGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-10-29 | — | — | WO | disclosed |
| US-5155110-A | Antiinflammatory agents, analgesics, antipyretics | WARNER-LAMBERT COMPANY (US) | 1992-10-13 | — | — | US | disclosed |
| WO-1989003818-A1 | NOVEL FENAMIC ACID HYDROXAMATE DERIVATIVES HAVING CYCLOOXYGENASE AND 5-LIPOXYGENASE INHIBITION | WARNER-LAMBERT COMPANY (US) | 1989-05-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240294493-A1 | GluN2C/D Subunit Selective Antagonists of the N-Methyl-D-Aspartate Receptor | GRIN2C, GRIN2A, GRIN2B | ALDH1A1 1930/4885HSD17B10 3000/4885CFTR 4314/4885 |
| US-20100113475-A1 | PYRAZOLYLAMINOPYRIDINES AS INHIBITORS OF FAK | PTK2, PAK1, CTTN | ALDH1A1 2365/4885HSD17B10 4787/4885CFTR 793/4885 |
| US-12391664-B2 | GluN2C/D subunit selective antagonists of the N-methyl-D-aspartate receptor | GRIN2C, GRIN2A, GRIN2B | ALDH1A1 1930/4885HSD17B10 3000/4885CFTR 4314/4885 |
| US-11981652-B2 | GluN2C/D subunit selective antagonists of the N-methyl-D-aspartate receptor | GRIN2C, GRIN2A, GRIN2B | ALDH1A1 1930/4885HSD17B10 3000/4885CFTR 4314/4885 |
| US-11981665-B2 | Substituted pyrimidines, pharmaceutical compositions and therapeutic methods thereof | BTK, PTK2, LCK | ALDH1A1 3348/4885HSD17B10 4831/4885CFTR 528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.