Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 4/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 2/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24420550 | 0.81 | DDR1 (0.43) | TRPV4GABRA1GABRB1HTTLMNA | |
| SCHEMBL21171934 | 0.81 | TRPV4 (0.53) | TRPV4HTTLMNACCR2PSEN1 | |
| SCHEMBL30714189 | 0.79 | TRPV4 (0.40) | TRPV4GABRA1GABRB1LMNAFABP4 | |
| SCHEMBL2814134 | 0.79 | TRPV4 (0.40) | TRPV4GABRA1GABRB1LMNAFABP4 | |
| SCHEMBL2814293 | 0.79 | PSEN1 (0.44) | TRPV4CCR2PSEN1PSEN2APH1B | |
| SCHEMBL7027875 | 0.75 | TRPV4 (0.37) | TRPV4GABRA1GABRB1FABP4MEN1 | |
| SCHEMBL30534761 | 0.75 | TRPV4 (0.37) | TRPV4GABRA1GABRB1FABP4MEN1 | |
| SCHEMBL31726245 | 0.75 | TRPV4 (0.57) | TRPV4CNR2PTGDR2 | |
| SCHEMBL21507979 | 0.75 | CCR2 (0.51) | LMNACNR2CCR2KMT2A | |
| SCHEMBL11856274 | 0.74 | TRPV4 (0.42) | TRPV4GABRA1GABRB1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8334410-B2 | Method for producing 3-mercaptoaniline compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2012-12-18 | — | — | US | disclosed |
| US-20100249462-A1 | METHOD FOR PRODUCING 3-MERCAPTOANILINE COMPOUND | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249462-A1 | METHOD FOR PRODUCING 3-MERCAPTOANILINE COMPOUND | TST, SULT2A1, SULT1E1 | TRPV4 2891/4885GABRA1 2590/4885GABRB1 3334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.