Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 6/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 6/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 6/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 6/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 6/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 6/20 | 0.44 |
| ▸ | TRPV4 | Q9HBA0 | 4/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18929871 | 0.83 | PSEN1 (0.41) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL2810380 | 0.79 | TRPV4 (0.53) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL30714189 | 0.78 | TRPV4 (0.40) | TRPV4SMN1; SMN2 | |
| SCHEMBL2814134 | 0.78 | TRPV4 (0.40) | TRPV4SMN1; SMN2 | |
| SCHEMBL4617330 | 0.77 | HTR2A (0.43) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL29764212 | 0.75 | TSHR (0.47) | TRPV4RXFP1 | |
| SCHEMBL181280 | 0.75 | TSHR (0.47) | TRPV4RXFP1 | |
| SCHEMBL5757186 | 0.74 | PSEN1 (0.47) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL7027875 | 0.74 | TRPV4 (0.37) | TRPV4 | |
| SCHEMBL113810 | 0.74 | AKR1B1 (0.46) | TRPV4CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8334410-B2 | Method for producing 3-mercaptoaniline compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2012-12-18 | — | — | US | disclosed |
| US-20100249462-A1 | METHOD FOR PRODUCING 3-MERCAPTOANILINE COMPOUND | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249462-A1 | METHOD FOR PRODUCING 3-MERCAPTOANILINE COMPOUND | TST, SULT2A1, SULT1E1 | PSEN1 4251/4885PSEN2 4454/4885APH1B 2557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.