Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL28254293 | 0.89 | — | — | |
| Succinic Acid SCHEMBL28385886 | 0.68 | BRD4 (0.33) | — | |
| SCHEMBL29919314 | 0.67 | ALDH1A1 (0.39) | — | |
| Succinic Acid SCHEMBL27647000 | 0.67 | EGLN1 (0.43) | APEX1 | |
| Sebacic Acid SCHEMBL28583209 | 0.66 | GPR84 (0.44) | — | |
| SCHEMBL1901288 | 0.65 | KMT2A (0.33) | APEX1 | |
| Dimethyl Succinate SCHEMBL1846318 | 0.65 | TSHR (0.42) | — | |
| Succinic Acid SCHEMBL29554976 | 0.63 | LMNA (0.31) | — | |
| SCHEMBL6938697 | 0.61 | — | — | |
| SCHEMBL10748882 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106103612-A | Fluoro-containing coating compositions and article | 旭硝子株式会社 | 2016-11-09 | — | — | CN | disclosed |