SCHEMBL28107366

SCHEMBL28107366

CC(C)(C)c1ccccc1B(O)O.COOB(O)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 4/20 0.37
CA4 P22748 1/20 0.35
CA6 P23280 1/20 0.35
CA5A P35218 1/20 0.35
CA7 P43166 1/20 0.35
CA14 Q9ULX7 1/20 0.35
CA5B Q9Y2D0 1/20 0.35
TDP1 Q9NUW8 2/20 0.35
ALDH1A1 P00352 1/20 0.35
TSHR P16473 1/20 0.35
ORAI1 Q96D31 2/20 0.33
ORAI2 Q96SN7 2/20 0.33
ORAI3 Q9BRQ5 2/20 0.33
CA2 P00918 2/20 0.32
LIPE Q05469 1/20 0.32
PCSK9 Q8NBP7 1/20 0.31
TRPV6 Q9H1D0 1/20 0.31
ATM Q13315 1/20 0.31
CA1 P00915 1/20 0.31
RBP4 P02753 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL262207 0.81 ENPP2 (0.46) ENPP2CA4CA6CA5ACA7
Fluoride SCHEMBL28835775 0.79 ENPP2 (0.44) ENPP2CA4CA6CA5ACA7
SCHEMBL30038787 0.79 ALDH1A1 (0.52) ENPP2CA4CA6CA5ACA7
SCHEMBL26450 0.79 ALDH1A1 (0.52) ENPP2CA4CA6CA5ACA7
SCHEMBL1507181 0.74 TDP1 (0.46) ENPP2CA4CA6CA5ACA7
SCHEMBL7546619 0.74 TDP1 (0.41) ENPP2CA4CA6CA5ACA7
SCHEMBL3426499 0.74 ALDH1A1 (0.46) ENPP2CA4CA6CA5ACA7
SCHEMBL28107367 0.73 ENPP2 (0.71) ENPP2CA4CA7CA14TDP1
SCHEMBL3419277 0.71 ENPP2 (0.43) ENPP2TDP1ALDH1A1TSHRORAI1
SCHEMBL4055347 0.70 ENPP2 (0.37) ENPP2TDP1ALDH1A1ORAI1ORAI2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106117256-A β phenanthro-azepine fluorine boron two pyrylium dyes and its preparation method and application 安徽师范大学 2016-11-16 CN disclosed