SCHEMBL26450

SCHEMBL26450

CC(C)(C)c1ccccc1B(O)O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.52
TSHR P16473 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
CA2 P00918 1/20 0.48
ENPP2 Q13822 2/20 0.43
GABRA1 P14867 1/20 0.41
GABRB2 P47870 1/20 0.41
RBP4 P02753 1/20 0.37
ORAI1 Q96D31 1/20 0.37
ORAI2 Q96SN7 1/20 0.37
ORAI3 Q9BRQ5 1/20 0.37
LIPG Q9Y5X9 1/20 0.36
CA4 P22748 1/20 0.36
CA6 P23280 1/20 0.36
CA5A P35218 1/20 0.36
CA7 P43166 1/20 0.36
CA14 Q9ULX7 1/20 0.36
CA5B Q9Y2D0 1/20 0.36
KIF11 P52732 1/20 0.35
LIPE Q05469 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30038787 1.00 ALDH1A1 (0.52) ALDH1A1TSHRTDP1CA2ENPP2
SCHEMBL1507181 0.93 TDP1 (0.46) ALDH1A1TSHRTDP1CA2ENPP2
SCHEMBL3426499 0.93 ALDH1A1 (0.46) ALDH1A1TSHRTDP1CA2ENPP2
SCHEMBL28107367 0.84 ENPP2 (0.71) ALDH1A1TSHRTDP1CA2ENPP2
SCHEMBL15011081 0.83 ENPP2 (0.41) ALDH1A1TSHRTDP1CA2ENPP2
SCHEMBL3419277 0.82 ENPP2 (0.43) ALDH1A1TSHRTDP1CA2ENPP2
SCHEMBL6048537 0.81 ENPP2 (0.40) ALDH1A1TSHRTDP1CA2ENPP2
SCHEMBL20975383 0.81 ENPP2 (0.40) ALDH1A1TSHRTDP1CA2ENPP2
SCHEMBL31360869 0.79 CA2 (0.48) ALDH1A1TSHRTDP1CA2ENPP2
SCHEMBL28107366 0.79 ENPP2 (0.37) ALDH1A1TSHRTDP1CA2ENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 239 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118005471-A Novel method for synthesizing 4-tert-butyl biphenyl by using palladium to catalyze tetrafluorothianthrene salt 内蒙古大学 2024-05-10 CN claimed
CN-110523354-A A kind of preparation method of the microreactor containing solid-carried catalyst UNIV ZHEJIANG 2019-12-03 CN claimed
CN-109134342-A The high efficiency preparation method of one kind 3,4- disubstituted pyrroles 大连理工大学 2019-01-04 CN claimed
CN-108794518-A It is a kind of using BODIPY as organic conjugated molecule material of basic framework and preparation method thereof 安徽师范大学 2018-11-13 CN claimed
CN-105198690-B The preparation method of the various positions substitution compound of fluorene class of halogen regulation and control 南京邮电大学 2017-11-14 CN claimed
CN-104844400-B Preparation method for 9-fluorenone and T type oligomeric phenylene skeleton compounds 南京邮电大学 2017-03-22 CN claimed
CN-106117256-A β phenanthro-azepine fluorine boron two pyrylium dyes and its preparation method and application 安徽师范大学 2016-11-16 CN claimed
CN-105732574-A Preparation of thianthrene-5, 5,10, 10-tetraoxide derivative and organic electroluminescent device based on thianthrene-5, 5,10, 10-tetraoxide derivative 中国科学院理化技术研究所 2016-07-06 CN claimed
CN-105693608-A 2, 2-dimethyl-1, 3-indene dione derivatives and organic electroluminescent devices based thereon 中国科学院理化技术研究所 2016-06-22 CN claimed
CN-105198690-A Preparation method of all-position replacement fluorene compounds obtained through halogen adjustment and control UNIV NANJING POSTS & TELECOMM 2015-12-30 CN claimed
CN-104844400-A Preparation method for 9-fluorenone and T type oligomeric phenylene skeleton compounds UNIV NANJING POSTS & TELECOMM 2015-08-19 CN claimed
CN-104498025-A Polyphenyl benzene structured cyanogroup-containing luminescent molecule and preparation method and purpose thereof UNIV WUHAN 2015-04-08 CN claimed
US-12630566-B2 KRas G12D inhibitors Mirati Therapeutics, Inc. (US) 2026-05-19 US disclosed
CN-122010899-A Continuous flow preparation method of lenalidomide and derivatives thereof 深圳连续制药科技有限公司 2026-05-12 CN disclosed
US-12509480-B2 Organometallic complex, light emitting diode, and electronic device KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2025-12-30 US disclosed
US-20250234703-A1 Organic Compound And Organic Light-Emitting Element Comprising Same P&H TECH CO., LTD (KR) 2025-07-17 US disclosed
US-20030009046-A1 Preparation of preparing substituted indanones EQUISTAR CHEMICALS, LP 2003-01-09 US disclosed
EP-1242434-A1 POLYMERIZATION-ACTIVE TRANSITION METAL COMPLEX COMPOUNDS COMPRISING A STERICALLY DEMANDING LIGAND SYSTEM BASF AKTIENGESELLSCHAFT (DE) 2002-09-25 EP disclosed
EP-0832082-B1 N-HETEROARYL-PYRIDINESULFONAMIDE DERIVATIVES AND THEIR USE AS ENDOTHELIN ANTAGONISTS ASTRAZENECA AB (SE) 2001-11-21 EP disclosed
WO-2001042257-A1 POLYMERIZATION-ACTIVE TRANSITION METAL COMPLEX COMPOUNDS COMPRISING A STERICALLY DEMANDING LIGAND SYSTEM BASF AKTIENGESELLSCHAFT (DE) 2001-06-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12630566-B2 KRas G12D inhibitors KRAS, NRAS, HRAS ALDH1A1 1816/4885TSHR 4213/4885TDP1 3446/4885
US-12509480-B2 Organometallic complex, light emitting diode, and electronic device GRK1, CRY1, NR2E3 ALDH1A1 53/4885TSHR 2295/4885TDP1 2897/4885
US-20250234703-A1 Organic Compound And Organic Light-Emitting Element Comprising Same CRY2, CRY1, RBP4 ALDH1A1 584/4885TSHR 4594/4885TDP1 2470/4885
US-20030009046-A1 Preparation of preparing substituted indanones CYP1A2, CYP1B1, CYP1A1 ALDH1A1 198/4885TSHR 4667/4885TDP1 3321/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.