Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 4/20 | 0.41 |
| ▸ | MAP3K9 | P80192 | 1/20 | 0.39 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.39 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 4/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | PNPLA2 | Q96AD5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31344196 | 0.86 | ALDH1A1 (0.51) | KDM4EMEN1NPC1ALDH1A1MAPT | |
| SCHEMBL29271841 | 0.74 | MEN1 (0.40) | KDM4EMEN1NPC1ALDH1A1MAPT | |
| SCHEMBL29672082 | 0.74 | LMNA (0.50) | KDM4EMEN1NPC1ALDH1A1MAPT | |
| SCHEMBL22067694 | 0.73 | MAP3K9 (0.55) | KDM4ENPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL29355432 | 0.73 | MAP3K9 (0.55) | KDM4ENPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL30741433 | 0.73 | MAP3K9 (0.55) | KDM4ENPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL31192163 | 0.71 | ALDH1A1 (0.54) | KDM4EMEN1NPC1ALDH1A1MAPT | |
| SCHEMBL7980286 | 0.71 | ALDH1A1 (0.54) | KDM4EMEN1NPC1ALDH1A1MAPT | |
| SCHEMBL2299077 | 0.70 | ADORA1 (0.50) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL18203498 | 0.69 | DRD2 (0.36) | ALDH1A1MAPTRAB9ASMN1; SMN2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106046363-B | One kind is containing fluorene structured high dissolubility Nomex of tetramethoxy and preparation method thereof | 常州大学 | 2019-01-25 | — | — | CN | claimed |
| CN-106046363-A | Tetramethoxyfluorene-structure-containing high-solubility polyaryl amides and preparation method thereof | 常州大学 | 2016-10-26 | — | — | CN | claimed |
| CN-106046363-A | Tetramethoxyfluorene-structure-containing high-solubility polyaryl amides and preparation method thereof | 常州大学 | 2016-10-26 | — | — | CN | disclosed |