Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31192163 | 1.00 | ALDH1A1 (0.54) | ALDH1A1RAB9AKDM4ESMN1; SMN2MAPT | |
| Methane SCHEMBL28300119 | 0.98 | ALDH1A1 (0.52) | ALDH1A1RAB9AKDM4ESMN1; SMN2MAPT | |
| SCHEMBL28340252 | 0.83 | KDM4E (0.54) | ALDH1A1RAB9AKDM4ESMN1; SMN2MAPT | |
| SCHEMBL29672082 | 0.81 | LMNA (0.50) | ALDH1A1RAB9AKDM4ESMN1; SMN2MAPT | |
| SCHEMBL8854649 | 0.80 | DRD2 (0.54) | ALDH1A1RAB9AKDM4ESMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL7201361 | 0.80 | KDM4E (0.51) | ALDH1A1RAB9AKDM4ESMN1; SMN2MAPT | |
| SCHEMBL9367661 | 0.79 | KDM4E (0.47) | ALDH1A1KDM4ESMN1; SMN2MAPTCA1 | |
| SCHEMBL7941151 | 0.79 | KDM4E (0.50) | ALDH1A1RAB9AKDM4ESMN1; SMN2MAPT | |
| SCHEMBL28841162 | 0.79 | KDM4E (0.50) | ALDH1A1RAB9AKDM4ESMN1; SMN2MAPT | |
| SCHEMBL28305794 | 0.79 | PTGS2 (0.46) | ALDH1A1RAB9AKDM4ESMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023351-A | Main catalyst composition prepared by combining internal electron donors | 格雷斯公司 | 2019-07-16 | — | — | CN | claimed |
| CN-106543310-B | A kind of olefin polymerization catalyst system and its application | 中国石油化工股份有限公司 | 2019-06-28 | — | — | CN | claimed |
| CN-109890850-A | Process for preparing a solid support for a procatalyst suitable for olefin polymerization | SABIC环球技术有限责任公司 | 2019-06-14 | — | — | CN | claimed |
| CN-109790251-A | Process for preparing procatalyst for olefin polymerization | SABIC环球技术有限责任公司 | 2019-05-21 | — | — | CN | claimed |
| CN-109661385-A | Method for synthesizing bis- (methylol) fluorenes of 9,9- | SABIC环球技术有限责任公司 | 2019-04-19 | — | — | CN | claimed |
| CN-105440185-B | A kind of loaded catalyst and preparation method thereof and its method for being used for propylene polymerization | 万华化学集团股份有限公司 | 2019-04-19 | — | — | CN | claimed |
| CN-109438596-A | Catalyst, preparation method, using polyalcohol stephanoporate microballoons as the catalyst system of carrier and application method | 中国科学院长春应用化学研究所 | 2019-03-08 | — | — | CN | claimed |
| CN-106916405-B | A kind of polybutene thermoplastic elastomer (TPE) and preparation method thereof | 青岛科技大学 | 2019-02-05 | — | — | CN | claimed |
| CN-104558290-B | One kind being used for catalyst component for olefin polymerization and catalyst | 中国石油化工股份有限公司 | 2018-11-02 | — | — | CN | claimed |
| CN-105934449-B | For the carbon monoxide-olefin polymeric of olefinic polymerization | 沙特基础工业公司 | 2018-07-10 | — | — | CN | claimed |
| CN-110498871-A | A kind of alkoxyl magnesium carrier granular and its application | SHANGHAI RES INSTITUTE OF CHEMICAL INDUSTRY CO LTD | 2019-11-26 | — | — | CN | disclosed |
| CN-105849179-B | Heterophasic propylene copolymers | 沙特基础工业公司 | 2019-11-12 | — | — | CN | disclosed |
| CN-110382555-A | Method for polyolefin polymerization | SABIC环球技术有限责任公司 | 2019-10-25 | — | — | CN | disclosed |
| CN-110283261-A | A kind of host component of olefin polymerization catalysis and preparation method thereof | 上海化工研究院有限公司 | 2019-09-27 | — | — | CN | disclosed |
| CN-106471018-B | The raw catalyst of polymerization for alkene | SABIC环球技术有限责任公司 | 2019-09-17 | — | — | CN | disclosed |
| CN-103073661-B | Magnesium dichloride-based adduct and catalytic component prepared therefrom | 巴塞尔聚烯烃意大利有限公司 | 2018-06-12 | — | — | CN | disclosed |
| CN-1659190-A | Process for the preparation of ethylene copolymers | BASELL POLIOLEFINE SPA (IT) | 2005-08-24 | — | — | CN | disclosed |
| US-6194439-B1 | ANTICANCER AGENT | PFIZER INC. | 2001-02-27 | — | — | US | disclosed |
| EP-0586608-A1 | TRICYCLIC POLYHYDROXYLIC TYROSINE KINASE INHIBITORS | PFIZER INC. (US) | 1994-03-16 | — | — | EP | disclosed |
| WO-1992021660-A1 | TRICYCLIC POLYHYDROXYLIC TYROSINE KINASE INHIBITORS | PFIZER, INC. (US) | 1992-12-10 | — | — | WO | disclosed |