Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 5/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ASAH1 | Q13510 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.45 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6381049 | 0.91 | TDP1 (0.48) | CYP11B1CYP11B2HTTSMN1; SMN2LMNA | |
| SCHEMBL20683088 | 0.76 | TDP1 (0.48) | CYP11B1CYP11B2HTTSMN1; SMN2LMNA | |
| SCHEMBL8013907 | 0.75 | TDP1 (0.52) | CYP11B1CYP11B2HTTSMN1; SMN2LMNA | |
| SCHEMBL273486 | 0.75 | TDP1 (0.52) | CYP11B1CYP11B2HTTSMN1; SMN2LMNA | |
| SCHEMBL1879818 | 0.73 | HTT (0.48) | CYP11B1CYP11B2HTTSMN1; SMN2LMNA | |
| SCHEMBL9060998 | 0.71 | TDP1 (0.48) | CYP11B1CYP11B2HTTSMN1; SMN2LMNA | |
| SCHEMBL8412995 | 0.70 | MEN1 (0.47) | CYP11B1CYP11B2HTTSMN1; SMN2LMNA | |
| SCHEMBL16401979 | 0.69 | TDP1 (0.46) | CYP11B1CYP11B2HTTSMN1; SMN2LMNA | |
| SCHEMBL8792548 | 0.69 | TDP1 (0.46) | CYP11B1CYP11B2HTTSMN1; SMN2LMNA | |
| SCHEMBL6529410 | 0.69 | CYP11B1 (0.53) | CYP11B1CYP11B2HTTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110229141-A | A kind of novel preparation method of high-purity esomeprazole sodium | 福安药业集团重庆博圣制药有限公司 | 2019-09-13 | — | — | CN | claimed |
| CN-106146460-A | The synthesis of a kind of Esomeprazole sodium and process for purification | 天津汉瑞药业有限公司 | 2016-11-23 | — | — | CN | claimed |