Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.51 |
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.47 |
| ▸ | TAS1R2 | Q8TE23 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12709415 | 0.79 | P2RX7 (0.61) | P2RX7RAB9AALDH1A1KDM4EGAA | |
| SCHEMBL16371875 | 0.75 | P2RX7 (0.47) | P2RX7TAS1R3TAS1R1TAS1R2RAB9A | |
| SCHEMBL17799694 | 0.75 | P2RX7 (0.47) | P2RX7TAS1R3TAS1R1TAS1R2RAB9A | |
| SCHEMBL9155166 | 0.74 | TAS1R3 (0.63) | TAS1R3TAS1R1TAS1R2ALDH1A1KDM4E | |
| SCHEMBL27761583 | 0.73 | ALDH1A1 (0.55) | ALDH1A1KDM4EGAATSHRSMN1; SMN2 | |
| SCHEMBL28111220 | 0.73 | P2RX7 (0.49) | P2RX7TAS1R3TAS1R1TAS1R2ALDH1A1 | |
| SCHEMBL16372250 | 0.72 | P2RX7 (0.43) | P2RX7TAS1R3TAS1R1TAS1R2ALDH1A1 | |
| SCHEMBL17799715 | 0.72 | P2RX7 (0.43) | P2RX7TAS1R3TAS1R1TAS1R2ALDH1A1 | |
| SCHEMBL9157091 | 0.71 | HSD11B1 (0.48) | TAS1R3TAS1R1TAS1R2RAB9AALDH1A1 | |
| SCHEMBL9153874 | 0.71 | TAS1R3 (0.44) | TAS1R3TAS1R1TAS1R2RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1703402-A | Pyridine derivatives as CB2 receptor modulators | GLAXO GROUP LTD (GB) | 2005-11-30 | — | — | CN | disclosed |