Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9755720 | 0.76 | ALDH1A1 (0.56) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL28114918 | 0.73 | ALDH1A1 (0.41) | ALDH1A1MAPTLMNAKDM4EKMT2A | |
| SCHEMBL29176394 | 0.70 | GAA (0.44) | ALDH1A1MAPTLMNAKDM4EMEN1 | |
| SCHEMBL9755721 | 0.70 | ALDH1A1 (0.50) | ALDH1A1MAPTLMNAKDM4EMEN1 | |
| SCHEMBL27419618 | 0.69 | HTR6 (0.47) | ALDH1A1MAPTHTR6LMNAKDM4E | |
| SCHEMBL927402 | 0.69 | ALDH1A1 (0.41) | ALDH1A1MAPTLMNAKDM4EMEN1 | |
| SCHEMBL9755727 | 0.68 | MEN1 (0.58) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL990746 | 0.68 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL1174173 | 0.68 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL9755713 | 0.67 | ALDH1A1 (0.46) | ALDH1A1LMNAGAAHPGDCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107021951-A | SGC stimulators | 铁木医药有限公司 | 2017-08-08 | — | — | CN | disclosed |
| CN-103313976-B | sGC stimulators | 铁木医药有限公司 | 2016-11-23 | — | — | CN | disclosed |