SCHEMBL990746

SCHEMBL990746

C=C(C(=O)OCC)S(C)(=O)=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.47
TSHR P16473 1/20 0.47
MAPT P10636 2/20 0.39
NPSR1 Q6W5P4 1/20 0.39
GLO1 Q04760 1/20 0.39
LMNA P02545 1/20 0.39
HSD17B10 Q99714 1/20 0.39
ALOX15 P16050 1/20 0.37
MGAM O43451 1/20 0.37
GAA P10253 1/20 0.37
SI P14410 1/20 0.37
MGAM2 Q2M2H8 1/20 0.37
SOAT1 P35610 1/20 0.37
THRB P10828 1/20 0.36
EGLN1 Q9GZT9 1/20 0.36
TRPA1 O75762 1/20 0.34
CYP2D6 P10635 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HPGD P15428 1/20 0.33
RECQL P46063 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1174173 0.82 ALDH1A1 (0.47) ALDH1A1TSHRMAPTNPSR1GLO1
SCHEMBL28372680 0.80 ALDH1A1 (0.45) ALDH1A1TSHRMAPTNPSR1GLO1
SCHEMBL5708086 0.78 ALDH1A1 (0.44) ALDH1A1TSHRMAPTNPSR1GLO1
SCHEMBL22832322 0.78 ALDH1A1 (0.44) ALDH1A1TSHRMAPTNPSR1GLO1
SCHEMBL27592399 0.78 ALDH1A1 (0.44) ALDH1A1TSHRMAPTNPSR1GLO1
SCHEMBL28026416 0.77 ALDH1A1 (0.42) ALDH1A1TSHRMAPTNPSR1GLO1
SCHEMBL29096077 0.77 ALDH1A1 (0.42) ALDH1A1TSHRMAPTNPSR1GLO1
SCHEMBL3951015 0.76 ALDH1A1 (0.45) ALDH1A1TSHRMAPTNPSR1GLO1
SCHEMBL18695287 0.75 ALDH1A1 (0.41) ALDH1A1TSHRMAPTNPSR1GLO1
SCHEMBL18203189 0.74 ALDH1A1 (0.48) ALDH1A1TSHRMAPTNPSR1GLO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060085922-A1 Oxidizing composition comprising at least one electrophilic monomer and at least one non-benzoquinone oxidant L'OREAL S.A. (FR) 2006-04-27 US claimed
CN-113943436-B Preparation method of solvent-resistant high-dielectric-constant insulating layer capable of being simply patterned 郑州大学 2023-06-02 CN disclosed
CN-113943436-A Preparation method of solvent-resistant high-dielectric-constant insulating layer capable of being patterned simply and conveniently 郑州大学 2022-01-18 CN disclosed
CN-111228124-A Rapid curing and low shrinkage stress photopolymerizable dental composites 义获嘉伟瓦登特公司 2020-06-05 CN disclosed
US-20120156270-A1 METHOD FOR SMOOTHING OUT THE SKIN BY FILLING IN RECESSED PORTIONS L'OREAL (FR) 2012-06-21 US disclosed
US-20120156270-A1 METHOD FOR SMOOTHING OUT THE SKIN BY FILLING IN RECESSED PORTIONS L'OREAL (FR) 2012-06-21 US disclosed
EP-2451536-A2 METHOD FOR SMOOTHING OUT THE SKIN BY FILLING IN RECESSED PORTIONS L'Oréal (FR) 2012-05-16 EP disclosed
WO-2011003771-A2 METHOD FOR SMOOTHING OUT THE SKIN BY FILLING IN RECESSED PORTIONS L'OREAL (FR) 2011-01-13 WO disclosed
US-20100172858-A1 COSMETIC COMPOSITION COMPRISING AT LEAST ONE POLYMER OBTAINED FROM A DIELECTROPHILIC MONOMER L'OREAL S.A. (FR) 2010-07-08 US disclosed
US-20100172858-A1 COSMETIC COMPOSITION COMPRISING AT LEAST ONE POLYMER OBTAINED FROM A DIELECTROPHILIC MONOMER L'OREAL S.A. (FR) 2010-07-08 US disclosed
CN-1762327-A Use for the cosmetic treatment of keratinous material of not sticky compositions based on electrophilic monomers and non-silicon polymers OREAL (FR) 2006-04-26 CN disclosed
US-20060083706-A1 Haircare composition comprising at least one electrophilic monomer and micro- or nanoparticles of at least one solid lubricant L'OREAL S.A. (FR) 2006-04-20 US disclosed
US-20060083762-A1 Uses of compositions comprising electrophilic monomers and micro-particles or nanoparticles L'OREAL S.A. (FR) 2006-04-20 US disclosed
US-20060080792-A1 Film-forming composition for the cosmetic treatment of keratin materials comprising at least one electrophilic monomer and at least one non-silicone polymer L'OREAL S.A. (FR) 2006-04-20 US disclosed
US-20060078523-A1 Composition comprising at least one electrophilic monomer and at least one acid in a cosmetically acceptable anhydrous medium, and use thereof for cosmetic treatment of the hair L'OREAL S.A. (FR) 2006-04-13 US disclosed
US-20060078522-A1 Composition for treating keratin materials comprising at least one electrophilic monomer and at least one salt L'OREAL S.A. (FR) 2006-04-13 US disclosed
US-6451947-B1 FOR USE IN MEDICAL DEVICES SUCH AS PACEMAKERS MEDTRONIC, INC. 2002-09-17 US disclosed
US-6184324-B1 CONTAINING ACRYLIC POLYMERS AS DIELECTRIC MATERIAL MEDTRONIC, INC. 2001-02-06 US disclosed
EP-0946953-A1 HIGH ENERGY DENSITY CAPACITORS AND COMPOUNDS FOR USE IN THEIR PREPARATION MEDTRONIC, INC. (US) 1999-10-06 EP disclosed
WO-1998027562-A1 HIGH ENERGY DENSITY CAPACITORS AND COMPOUNDS FOR USE IN THEIR PREPARATION MEDTRONIC, INC. (US) 1998-06-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060083762-A1 Uses of compositions comprising electrophilic monomers and micro-particles or nanoparticles KRT18, PRKDC, ACP1 ALDH1A1 828/4885TSHR 4297/4885MAPT 355/4885
US-20100172858-A1 COSMETIC COMPOSITION COMPRISING AT LEAST ONE POLYMER OBTAINED FROM A DIELECTROPHILIC MONOMER KRT18, DSG1, DSC1 ALDH1A1 320/4885TSHR 4403/4885MAPT 721/4885
US-20060085922-A1 Oxidizing composition comprising at least one electrophilic monomer and at least one non-benzoquinone oxidant KRT18, GPX4, NOX4 ALDH1A1 303/4885TSHR 4243/4885MAPT 2098/4885
US-20060083706-A1 Haircare composition comprising at least one electrophilic monomer and micro- or nanoparticles of at least one solid lubricant MITF, CUTA, NACA ALDH1A1 43/4885TSHR 3327/4885MAPT 865/4885
US-20060078523-A1 Composition comprising at least one electrophilic monomer and at least one acid in a cosmetically acceptable anhydrous medium, and use thereof for cosmetic treatment of the hair HOGA1, OAT, SUCLG1 ALDH1A1 18/4885TSHR 4459/4885MAPT 1711/4885
US-20060078522-A1 Composition for treating keratin materials comprising at least one electrophilic monomer and at least one salt KRT18, DSG1, DSC1 ALDH1A1 1453/4885TSHR 4360/4885MAPT 215/4885
US-20120156270-A1 METHOD FOR SMOOTHING OUT THE SKIN BY FILLING IN RECESSED PORTIONS EPAS1, PGF, PASK ALDH1A1 4610/4885TSHR 4804/4885MAPT 4165/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.