Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 2/20 | 0.37 |
| ▸ | MMP12 | P39900 | 2/20 | 0.37 |
| ▸ | MMP13 | P45452 | 2/20 | 0.37 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11836425 | 0.94 | F2 (0.44) | DAOTDP1ALDH1A1F2SMN1; SMN2 | |
| SCHEMBL27679118 | 0.80 | CYP2A6 (0.52) | ALDH1A1LMNAMAPK1SMN1; SMN2KMT2A | |
| SCHEMBL20302244 | 0.75 | — | — | |
| SCHEMBL19269 | 0.74 | KMT2A (0.46) | TDP1ALDH1A1LMNAMAPK1SMN1; SMN2 | |
| Benzene SCHEMBL11355839 | 0.71 | ALDH1A1 (0.47) | TDP1ALDH1A1HSD17B10SMN1; SMN2TSHR | |
| Benzene SCHEMBL28311116 | 0.71 | ALDH1A1 (0.47) | TDP1ALDH1A1HSD17B10SMN1; SMN2TSHR | |
| Benzene SCHEMBL107628 | 0.71 | ALDH1A1 (0.47) | TDP1ALDH1A1HSD17B10SMN1; SMN2TSHR | |
| Chlorobenzene SCHEMBL231594 | 0.71 | TSHR (0.69) | TDP1ALDH1A1HSD17B10LMNAMAPK1 | |
| 1,2-Dichlorobenzene SCHEMBL3864366 | 0.71 | TSHR (0.62) | TDP1ALDH1A1HSD17B10LMNASMN1; SMN2 | |
| SCHEMBL16937291 | 0.69 | KMT2A (0.43) | DAOALDH1A1F2LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106279041-A | Phenyl pyrimidine derivative and its production and use | 四川思睿博生物科技有限公司 | 2017-01-04 | — | — | CN | disclosed |