Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 12/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28836147 | 0.76 | CNR2 (0.60) | CNR2SMN1; SMN2TSHRNPC1RAB9A | |
| SCHEMBL28111736 | 0.73 | CNR2 (1.00) | CNR2SMN1; SMN2TSHRNPC1RAB9A | |
| SCHEMBL1330727 | 0.71 | HSD11B1 (0.52) | CNR2NPC1RAB9AHSD11B1 | |
| SCHEMBL23269595 | 0.67 | HDAC3 (0.62) | SMN1; SMN2TSHRNPC1RAB9A | |
| SCHEMBL31759167 | 0.67 | BMPR1B (0.45) | CNR2SMN1; SMN2TSHR | |
| SCHEMBL31759235 | 0.65 | BMPR1B (0.43) | CNR2TSHRLMNA | |
| SCHEMBL26898604 | 0.65 | ALDH1A1 (0.58) | CNR2SMN1; SMN2TSHRNPC1RAB9A | |
| SCHEMBL28111774 | 0.65 | HSD11B1 (0.66) | CNR2SMN1; SMN2NPC1RAB9AHSD11B1 | |
| SCHEMBL1014719 | 0.64 | POLB (0.53) | CNR2SMN1; SMN2TSHRLMNAHSD11B1 | |
| SCHEMBL1013784 | 0.64 | POLB (0.53) | CNR2SMN1; SMN2TSHRLMNAHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106187910-A | Pyridazine class derivant and its production and use | 浙江大学 | 2016-12-07 | — | — | CN | claimed |
| CN-106187910-A | Pyridazine class derivant and its production and use | 浙江大学 | 2016-12-07 | — | — | CN | disclosed |