Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.60 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.48 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28111732 | 0.76 | CNR2 (0.78) | CNR2HSD11B1SMN1; SMN2LMNATSHR | |
| SCHEMBL28111774 | 0.75 | HSD11B1 (0.66) | CNR2HSD11B1SMN1; SMN2MEN1CYP1A2 | |
| SCHEMBL2591980 | 0.68 | HSD11B1 (1.00) | CNR2HSD11B1SMN1; SMN2MEN1CYP1A2 | |
| SCHEMBL28836519 | 0.68 | CNR2 (0.53) | CNR2LMNATSHRMEN1CYP1A2 | |
| SCHEMBL22565386 | 0.67 | ACKR3 (0.61) | CNR2HSD11B1SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL22449359 | 0.66 | ALDH1A1 (0.64) | HSD11B1SMN1; SMN2TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL1014776 | 0.66 | POLB (0.64) | HSD11B1SMN1; SMN2LMNAMEN1CYP1A2 | |
| SCHEMBL1017870 | 0.66 | POLB (0.64) | HSD11B1SMN1; SMN2LMNAMEN1CYP1A2 | |
| SCHEMBL12590352 | 0.66 | POLB (0.66) | CNR2SMN1; SMN2TSHRCYP1A2CYP3A4 | |
| SCHEMBL704712 | 0.65 | TAS1R3 (1.00) | SMN1; SMN2TAS1R3TAS1R1TAS1R2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106187910-A | Pyridazine class derivant and its production and use | 浙江大学 | 2016-12-07 | — | — | CN | claimed |
| CN-106187910-A | Pyridazine class derivant and its production and use | 浙江大学 | 2016-12-07 | — | — | CN | disclosed |