Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 8/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.34 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.34 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.34 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28330130 | 0.82 | MIF (0.41) | POLBMCHR1KCNH2TUBB4ATUBB | |
| 1,4-Dichlorobenzene SCHEMBL27842897 | 0.73 | HSD17B10 (0.42) | MEN1KMT2APOLBMAPTTHRB | |
| SCHEMBL28878285 | 0.70 | NOTUM (0.38) | MCHR1KCNH2TUBB4ATUBBTUBA3C | |
| SCHEMBL19625423 | 0.69 | NOTUM (0.40) | MEN1KMT2APOLBKCNH2TUBB4A | |
| SCHEMBL20097534 | 0.68 | MGLL (0.41) | MEN1KMT2APOLBRECQLMCHR1 | |
| Ethoxycarbonyl Group SCHEMBL28282915 | 0.68 | L3MBTL1 (0.46) | MEN1KMT2AMAPTALDH1A1TDP1 | |
| Ethoxycarbonyl Group SCHEMBL28284409 | 0.66 | POLB (0.45) | KMT2APOLBMAPTALDH1A1KDM4E | |
| SCHEMBL16077984 | 0.66 | FFAR4 (0.53) | — | |
| Chlorobenzene SCHEMBL28088147 | 0.65 | TSHR (0.46) | MEN1KMT2APOLBMAPTTHRB | |
| SCHEMBL31013537 | 0.65 | ALDH1A1 (0.46) | MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106061943-A | Bicyclic pyrrole derivatives useful as agonists of GPR120 | 詹森药业有限公司 | 2016-10-26 | — | — | CN | disclosed |