Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 8/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 2/20 | 0.33 |
| ▸ | Q9HBH1 | 1/20 | 0.32 | |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.32 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitric Acid SCHEMBL6072991 | 0.88 | CA5A (0.33) | TSHR | |
| Nitric Acid SCHEMBL28217021 | 0.86 | CA5A (0.32) | TSHR | |
| Phosphoric Acid SCHEMBL28181273 | 0.83 | FDPS (0.46) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| Nitric Acid SCHEMBL28345264 | 0.80 | DNM1 (0.57) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| Nitric Acid SCHEMBL25341518 | 0.78 | DNM1 (0.62) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| Nitric Acid SCHEMBL11504036 | 0.78 | DNM1 (0.62) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| Nitric Acid SCHEMBL9444046 | 0.78 | DNM1 (0.62) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| Nitric Acid SCHEMBL9818042 | 0.78 | DNM1 (0.62) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| Tetradecylamine SCHEMBL8731499 | 0.78 | DNM1 (0.62) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| Dodecylamine SCHEMBL9551516 | 0.78 | DNM1 (0.62) | DNM1ALDH1A1MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109880216-A | HDPE double-wall corrugated pipe and its production technology | 陕西飞天管业科技有限公司 | 2019-06-14 | — | — | CN | claimed |
| CN-106283752-A | A kind of anti-fouling and self-cleaning antistatic founds velvet and processing technique thereof | 浙江恒生印染有限公司 | 2017-01-04 | — | — | CN | claimed |