SCHEMBL2811298

SCHEMBL2811298

C=C(CCCC(=C)C(=O)NCC)C(=O)NCC

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 2/20 0.40
KMT2A Q03164 2/20 0.38
MMP1 P03956 1/20 0.34
MMP2 P08253 1/20 0.34
MMP3 P08254 1/20 0.34
MMP9 P14780 1/20 0.34
MMP8 P22894 1/20 0.34
PLAAT3 P53816 1/20 0.34
PLAAT5 Q96KN8 1/20 0.34
PLAAT2 Q9NWW9 1/20 0.34
PLAAT4 Q9UL19 1/20 0.34
TSHR P16473 1/20 0.33
HTT P42858 1/20 0.32
MCL1 Q07820 1/20 0.32
MAPT P10636 1/20 0.32
HDAC3 O15379 1/20 0.31
HDAC4 P56524 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC7 Q8WUI4 1/20 0.31
HDAC2 Q92769 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11238049 0.92 FAAH (0.35) FAAHKMT2AMMP1MMP2MMP3
SCHEMBL28890853 0.91 FAAH (0.47) FAAHKMT2AALDH1A1PLA2G2ACASP2
SCHEMBL5693537 0.87 CYP1A2 (0.39) FAAHKMT2AMMP1MMP2MMP3
SCHEMBL720662 0.87 FAAH (0.59) FAAHKMT2ATSHRHDAC11MEN1
SCHEMBL20379712 0.86 FAAH (0.40) FAAHKMT2AMMP1MMP2MMP3
SCHEMBL27839076 0.84 KMT2A (0.37) FAAHKMT2AMMP1MMP2MMP3
SCHEMBL5693389 0.82 KMT2A (0.35) FAAHKMT2AMMP1MMP2MMP3
SCHEMBL7936208 0.80
SCHEMBL11238055 0.80
SCHEMBL21450442 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2226061-B2 Infiltrant for dental application ERNST MÜHLBAUER GMBH & CO KG (DE) 2017-01-25 EP claimed
US-9211236-B2 Infiltrant for dental application MUHLBAUER GMBH & CO. KG (DE) 2015-12-15 US claimed
US-20130116384-A1 INFILTRANT FOR DENTAL APPLICATION ERNST MUHLBAUER GMBH & CO. KG (DE) 2013-05-09 US claimed
EP-2226061-B1 Infiltrant for dental application MUEHLBAUER ERNST GMBH & CO KG (DE) 2012-12-26 EP claimed
US-20100240853-A1 INFILTRANT FOR DENTAL APPLICATION ERNST MÜHLBAUER GMBH & CO. KG (DE) 2010-09-23 US claimed
EP-3530257-B1 SELF-ADHESIVE DENTAL COMPOSITE RESIN KURARAY NORITAKE DENTAL INC (JP) 2021-09-08 EP disclosed
US-10987281-B2 Self-adhesive dental composite resin KURARAY NORITAKE DENTAL INC. (JP) 2021-04-27 US disclosed
US-20200179237-A1 SELF-ADHESIVE DENTAL COMPOSITE RESIN KURARAY NORITAKE DENTAL INC. (JP) 2020-06-11 US disclosed
EP-3530257-A1 SELF-ADHESIVE DENTAL COMPOSITE RESIN Kuraray Noritake Dental Inc. (JP) 2019-08-28 EP disclosed
US-10058487-B2 Polymerizable dental material MUHLBAUER TECHNOLOGY GMBH (DE) 2018-08-28 US disclosed
US-9901519-B2 Infiltrant for dental ceramics MUHLBAUER TECHNOLOGY GMBH (DE) 2018-02-27 US disclosed
US-20170065496-A1 POLYMERIZABLE DENTAL MATERIAL MUHLBAUER TECHNOLOGY GMBH (DE) 2017-03-09 US disclosed
US-20160128908-A1 INFILTRANT FOR DENTAL CERAMICS MUHLBAUER TECHNOLOGY GMBH (DE) 2016-05-12 US disclosed
US-9211236-B2 Infiltrant for dental application MUHLBAUER GMBH & CO. KG (DE) 2015-12-15 US disclosed
US-20130116384-A1 INFILTRANT FOR DENTAL APPLICATION ERNST MUHLBAUER GMBH & CO. KG (DE) 2013-05-09 US disclosed
US-8362172-B2 Infiltrant for dental application ERNST MUHLBAUER GMBH & CO. KG (DE) 2013-01-29 US disclosed
US-20100240853-A1 INFILTRANT FOR DENTAL APPLICATION ERNST MÜHLBAUER GMBH & CO. KG (DE) 2010-09-23 US disclosed
US-4322491-A BINDER, PHOTOINITIATOR, AND AN UNSATURATED COMPOUND HOECHST AKTIENGESELLSCHAFT (DE) 1982-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10058487-B2 Polymerizable dental material EHD1, ESD, HPD FAAH 783/4885KMT2A 572/4885MMP1 4810/4885
US-10987281-B2 Self-adhesive dental composite resin SMCHD1, CDH1, SMC1A FAAH 4219/4885KMT2A 600/4885MMP1 3077/4885
US-20200179237-A1 SELF-ADHESIVE DENTAL COMPOSITE RESIN SMCHD1, CDH1, SMC1A FAAH 4219/4885KMT2A 600/4885MMP1 3077/4885
US-20170065496-A1 POLYMERIZABLE DENTAL MATERIAL EHD1, ESD, HPD FAAH 783/4885KMT2A 572/4885MMP1 4810/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.