Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9407799 | 1.00 | TDP1 (0.43) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL1011793 | 0.80 | POLB (0.40) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL8857304 | 0.80 | TDP1 (0.48) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL1484039 | 0.80 | POLB (0.48) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL8873860 | 0.76 | TDP1 (0.53) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL329146 | 0.75 | NPSR1 (0.41) | POLBHTTTSHRKDM4EMEN1 | |
| SCHEMBL1256483 | 0.75 | MTNR1A (0.49) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL31582668 | 0.75 | POLB (0.44) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL8365990 | 0.75 | TDP1 (0.52) | TDP1POLBAPEX1HTTTSHR | |
| Hydrochloric Acid SCHEMBL1229428 | 0.74 | MTNR1A (0.47) | TDP1POLBAPEX1HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230165759-A1 | DENTAL CURABLE COMPOSITION | TOKUYAMA DENTAL CORPORATION (JP) | 2023-06-01 | — | — | US | disclosed |
| EP-4166127-A1 | DENTAL CURABLE COMPOSITION | Tokuyama Dental Corporation (JP) | 2023-04-19 | — | — | EP | disclosed |
| EP-2548916-B2 | ORGANIC/INORGANIC COMPOSITE FILLER AND MANUFACTURING METHOD THEREFOR | TOKUYAMA DENTAL CORP (JP) | 2023-03-22 | — | — | EP | disclosed |
| US-20210196440-A1 | PHOTOPOLYMERIZATION DEVICE AND DENTAL PROSTHESIS MANUFACTURING KIT | TOKUYAMA DENTAL CORPORATION (JP) | 2021-07-01 | — | — | US | disclosed |
| US-11001713-B2 | Organic/inorganic composite filler and manufacturing method therefor | TOKUYAMA DENTAL CORPORATION (JP) | 2021-05-11 | — | — | US | disclosed |
| US-20180273766-A1 | Organic/Inorganic Composite Filler and Manufacturing Method Therefor | TOKUYAMA DENTAL CORPORATION (JP) | 2018-09-27 | — | — | US | disclosed |
| EP-2724706-B1 | DENTAL RESTORATIVE MATERIAL | TOKUYAMA DENTAL CORP (JP) | 2018-09-12 | — | — | EP | disclosed |
| US-10005910-B2 | Organic/inorganic composite filler and manufacturing method therefor | TOKUYAMA DENTAL CORPORATION (JP) | 2018-06-26 | — | — | US | disclosed |
| US-10004667-B2 | Organic-inorganic composite filler, and method for producing the same | TOKUYAMA DENTAL CORPORATION (JP) | 2018-06-26 | — | — | US | disclosed |
| US-9901519-B2 | Infiltrant for dental ceramics | MUHLBAUER TECHNOLOGY GMBH (DE) | 2018-02-27 | — | — | US | disclosed |
| WO-2007033288-A2 | COMPOSITE PASTE FOR DENTAL PROSTHESES | DANVILLE MATERIALS, INC. (US) | 2007-03-22 | — | — | WO | disclosed |
| US-7056961-B2 | Adhesive composition for denture base relining material and dental curable composition | TOKUYAMA CORPORATION (JP) | 2006-06-06 | — | — | US | disclosed |
| US-20040048948-A1 | Adhesive composition for denture base relining material and dental curable composition | TOKUYAMA DENTAL CORPORATION (JP) | 2004-03-11 | — | — | US | disclosed |
| EP-1348416-A1 | ADHESIVE COMPOSITIONS FOR BACK-COATING DENTAL PLATE AND HARDENING COMPOSITIONS FOR DENTAL USE | TOKUYAMA CORPORATION (JP) | 2003-10-01 | — | — | EP | disclosed |
| US-5856374-A | IRREGULARLY-SHAPED, SPHERICAL AND FINE INORGANIC PARTICLE FILLERS | TOKUYAMA CORPORATION (JP) | 1999-01-05 | — | — | US | disclosed |
| EP-0839511-A2 | Curable composition | TOKUYAMA CORPORATION (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5260476-A | Dental restoration | TOKUYAMA SODA KABUSHIKI KAISHA (JP) | 1993-11-09 | — | — | US | disclosed |
| US-5171763-A | A dental composite of a monomer containing poly(3,4-carboxylic benzoic acid and acrylic ester moities, an ion leachable filler and an initiator; high adhesion and strength; discoloration inhibition | TOKUYAMA SODA KABUSHIKI KAISHA (JP) | 1992-12-15 | — | — | US | disclosed |
| US-5091033-A | ADHESIVE FOR CERAMICS AND PROCESSES FOR THE BONDING OF CERAMICS USING SAME | MITSUI SEKIYU KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1992-02-25 | — | — | US | disclosed |
| EP-0252603-A2 | Adhesives for ceramics and processes for the bonding of ceramics using same | MITSUI SEKIYU KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-01-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10005910-B2 | Organic/inorganic composite filler and manufacturing method therefor | VCL, PIEZO1, ORAI1 | TDP1 2850/4885POLB 2436/4885APEX1 2508/4885 |
| US-20180273766-A1 | Organic/Inorganic Composite Filler and Manufacturing Method Therefor | VCL, PIEZO1, ORAI1 | TDP1 2850/4885POLB 2436/4885APEX1 2508/4885 |
| US-10004667-B2 | Organic-inorganic composite filler, and method for producing the same | CD68, CD44, VCL | TDP1 2091/4885POLB 1219/4885APEX1 1836/4885 |
| US-20040048948-A1 | Adhesive composition for denture base relining material and dental curable composition | TAS2R42, TAF1, CAD | TDP1 802/4885POLB 321/4885APEX1 463/4885 |
| US-11001713-B2 | Organic/inorganic composite filler and manufacturing method therefor | VCL, PIEZO1, ORAI1 | TDP1 2850/4885POLB 2436/4885APEX1 2508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.