Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28193189 | 0.82 | SIGMAR1 (0.44) | ALDH1A1CYP11B2MAPTKMT2AMEN1 | |
| SCHEMBL28137179 | 0.79 | KDM4E (0.45) | ALDH1A1TAAR1 | |
| SCHEMBL29868636 | 0.72 | NAAA (0.35) | — | |
| SCHEMBL27366560 | 0.71 | LMNA (0.42) | LMNAALDH1A1POLBCYP11B1CYP11B2 | |
| SCHEMBL32688445 | 0.71 | HCRTR1 (0.33) | ALDH1A1GAA | |
| SCHEMBL28322028 | 0.69 | L3MBTL1 (0.57) | ALDH1A1CYP1A2 | |
| SCHEMBL23290132 | 0.69 | — | — | |
| SCHEMBL28238610 | 0.67 | HTT (0.42) | ALDH1A1MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL28230095 | 0.67 | TSHR (0.37) | LMNAALDH1A1POLBMAPTKMT2A | |
| Water SCHEMBL28218487 | 0.67 | LMNA (0.44) | LMNAALDH1A1POLBCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106170553-A | Modified nucleic acid molecules and uses thereof | 现代治疗公司 | 2016-11-30 | — | — | CN | claimed |
| CN-106170553-A | Modified nucleic acid molecules and uses thereof | 现代治疗公司 | 2016-11-30 | — | — | CN | disclosed |