Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.36 |
| ▸ | CTSL | P07711 | 2/20 | 0.34 |
| ▸ | CTSB | P07858 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CTSH | P09668 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28103059 | 0.80 | CTSK (0.34) | CTSKCTSLCTSBMEN1KMT2A | |
| SCHEMBL18085416 | 0.76 | EPHX1 (0.48) | CTSKCTSLCTSBMEN1KMT2A | |
| SCHEMBL28113598 | 0.74 | CTSK (0.34) | CTSKCTSLCTSBMEN1KMT2A | |
| SCHEMBL27498107 | 0.74 | BRD4 (0.42) | MAPK1HTTMEN1KMT2AMAPT | |
| SCHEMBL28113592 | 0.72 | TSHR (0.42) | CTSKMEN1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL28113594 | 0.71 | TDP1 (0.38) | CTSKCTSLCTSBMEN1KMT2A | |
| SCHEMBL28045730 | 0.70 | CTSK (0.37) | CTSKCTSLCTSBMEN1KMT2A | |
| SCHEMBL27698547 | 0.69 | PNP (0.36) | CTSKPOLBCYP2C9CYP2C19BLM | |
| SCHEMBL28045695 | 0.69 | CTSK (0.34) | CTSKCTSLCTSBMEN1KMT2A | |
| SCHEMBL28095278 | 0.68 | CTSK (0.54) | CTSKCTSLCTSBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106304835-A | Sgc stimulant | 铁木医药有限公司 | 2017-01-04 | — | — | CN | disclosed |