Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | DAO | P14920 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 4/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18085416 | 0.81 | EPHX1 (0.48) | EPHX1CTSKMEN1KMT2ATAAR1 | |
| SCHEMBL28045695 | 0.79 | CTSK (0.34) | EPHX1CTSKMEN1KMT2ATAAR1 | |
| SCHEMBL28814855 | 0.76 | MMP2 (0.37) | DAOCTSKMEN1KMT2ATAAR1 | |
| SCHEMBL28113594 | 0.76 | TDP1 (0.38) | DAOLMNAALDH1A1CTSKGLA | |
| SCHEMBL28045730 | 0.75 | CTSK (0.37) | LMNAALDH1A1EPHX1CTSKMEN1 | |
| SCHEMBL27498107 | 0.74 | BRD4 (0.42) | TSHRLMNAALDH1A1HPGDMEN1 | |
| SCHEMBL28113598 | 0.74 | CTSK (0.34) | EPHX1CTSKMEN1KMT2ATAAR1 | |
| SCHEMBL27931420 | 0.73 | RAB9A (0.39) | ALDH1A1EPHX1HPGDKMT2A | |
| SCHEMBL27963119 | 0.73 | LMNA (0.45) | LMNACYP2C9 | |
| SCHEMBL28061404 | 0.71 | EPHX1 (0.35) | EPHX1CTSKMEN1KMT2ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106304835-A | Sgc stimulant | 铁木医药有限公司 | 2017-01-04 | — | — | CN | disclosed |