Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 9/20 | 0.58 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.51 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.51 |
| ▸ | PTGFR | P43088 | 1/20 | 0.51 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.51 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | APAF1 | O14727 | 1/20 | 0.50 |
| ▸ | TDP2 | O95551 | 1/20 | 0.50 |
| ▸ | NSD2 | O96028 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28793250 | 0.85 | CXCR3 (0.51) | HDAC3HDAC1HDAC2HDAC6KDM4E | |
| SCHEMBL27075244 | 0.84 | PDE2A (0.54) | PDE2APTGER4HDAC3HDAC1HDAC2 | |
| SCHEMBL19282949 | 0.80 | PDE2A (0.51) | PDE2APTGER4HDAC3HDAC1HDAC2 | |
| SCHEMBL10605790 | 0.79 | LMNA (0.51) | PDE2AHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL28114119 | 0.78 | HDAC1 (0.55) | NPC1RAB9AHDAC3HDAC1HDAC2 | |
| SCHEMBL23796172 | 0.77 | PDE2A (0.48) | PDE2APTGER4HDAC6PTGER2TBXA2R | |
| SCHEMBL30290147 | 0.77 | PDE2A (0.48) | PDE2APTGER4HDAC6PTGER2TBXA2R | |
| SCHEMBL15021087 | 0.76 | SLC6A9 (0.79) | — | |
| SCHEMBL16249346 | 0.76 | WDR91 (0.53) | PDE2AHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL9188439 | 0.75 | SLC6A9 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104487433-B | Triazolone compounds as mPGES-1 inhibitors | 格兰马克药品股份有限公司 | 2016-12-07 | — | — | CN | disclosed |