Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.34 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.31 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11296862 | 0.78 | OPRM1 (0.49) | HSD11B1OPRM1OPRL1SSTR1SSTR4 | |
| SCHEMBL16083425 | 0.71 | OPRM1 (0.47) | HSD11B1OPRM1OPRL1 | |
| SCHEMBL15897427 | 0.71 | HSD11B1 (0.38) | HSD11B1OPRM1OPRL1SSTR1SSTR4 | |
| SCHEMBL2469547 | 0.71 | MAOA (0.50) | HSD11B1OPRM1OPRL1 | |
| SCHEMBL30589493 | 0.71 | MAOA (0.50) | HSD11B1OPRM1OPRL1 | |
| SCHEMBL2470610 | 0.70 | SSTR1 (0.49) | HSD11B1SSTR1SSTR4 | |
| SCHEMBL4960187 | 0.68 | CYP17A1 (0.41) | CYP2C9CYP2C19 | |
| SCHEMBL28009767 | 0.68 | ALDH1A1 (0.49) | CYP2C19 | |
| Hydrochloric Acid SCHEMBL29416920 | 0.68 | HSD11B1 (0.43) | HSD11B1OPRM1OPRL1SSTR1SSTR4 | |
| SCHEMBL29417062 | 0.68 | HSD11B1 (0.43) | HSD11B1OPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104487433-B | Triazolone compounds as mPGES-1 inhibitors | 格兰马克药品股份有限公司 | 2016-12-07 | — | — | CN | disclosed |