Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.38 |
| ▸ | PRKACA | P17612 | 2/20 | 0.32 |
| ▸ | PRKACG | P22612 | 2/20 | 0.32 |
| ▸ | PRKACB | P22694 | 2/20 | 0.32 |
| ▸ | AKT1 | P31749 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.31 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | CCR7 | P32248 | 1/20 | 0.31 |
| ▸ | MPO | P05164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28325986 | 0.91 | HCAR3 (0.34) | AKR1B1DPP4 | |
| SCHEMBL28113597 | 0.84 | AKR1B1 (0.36) | AKR1B1PRKACAPRKACGPRKACBAKT1 | |
| SCHEMBL28113598 | 0.78 | CTSK (0.34) | — | |
| SCHEMBL27485646 | 0.77 | DPP4 (0.34) | AKR1B1AKT1DPP4MPO | |
| SCHEMBL27627222 | 0.75 | HCAR3 (0.30) | — | |
| SCHEMBL28325982 | 0.74 | HCAR3 (0.34) | AKR1B1DPP4 | |
| SCHEMBL28327134 | 0.74 | AKR1B1 (0.32) | AKR1B1DPP4 | |
| SCHEMBL28113601 | 0.74 | XPO1 (0.35) | — | |
| SCHEMBL28113602 | 0.73 | — | — | |
| SCHEMBL27977725 | 0.71 | AKR1B1 (0.33) | AKR1B1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106304835-A | Sgc stimulant | 铁木医药有限公司 | 2017-01-04 | — | — | CN | disclosed |