Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XPO1 | O14980 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.31 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28113109 | 0.82 | PDE4B (0.37) | XPO1CYP2D6CYP2C9ALOX15TSHR | |
| Fluorobenzene SCHEMBL27936510 | 0.77 | RAB9A (0.37) | XPO1 | |
| SCHEMBL28113663 | 0.74 | AKR1B1 (0.38) | — | |
| SCHEMBL27627222 | 0.73 | HCAR3 (0.30) | — | |
| SCHEMBL28325986 | 0.73 | HCAR3 (0.34) | PPARGPPARA | |
| SCHEMBL28542963 | 0.72 | PDE1B (0.39) | HCAR2TSHR | |
| SCHEMBL28113598 | 0.72 | CTSK (0.34) | HCAR2SLC1A1 | |
| SCHEMBL28272803 | 0.72 | CYP1A2 (0.31) | CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL27550516 | 0.71 | RAB9A (0.41) | MAPK1HPGD | |
| SCHEMBL28093265 | 0.71 | PIM1 (0.39) | XPO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106304835-A | Sgc stimulant | 铁木医药有限公司 | 2017-01-04 | — | — | CN | disclosed |