Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 3/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31547319 | 0.89 | BRD4 (0.41) | HPGDRAB9ASMN1; SMN2MAPTTSHR | |
| SCHEMBL27659674 | 0.78 | RAB9A (0.39) | HPGDALOX15RAB9ASMN1; SMN2USP2 | |
| SCHEMBL1155984 | 0.74 | TRIM24 (0.40) | HPGDALOX15RAB9ASMN1; SMN2USP2 | |
| SCHEMBL17280164 | 0.74 | NUDT1 (0.35) | TRPA1BRD4HTR7HTR1A | |
| SCHEMBL193781 | 0.74 | LRRK2 (0.41) | HPGDALOX15RAB9ASMN1; SMN2USP2 | |
| SCHEMBL19897390 | 0.73 | TSHR (0.50) | HPGDRAB9ASMN1; SMN2TSHRTRPA1 | |
| SCHEMBL11470567 | 0.71 | KDM4E (0.46) | MAPTTRPA1BRD4GRIA1CACNG8 | |
| SCHEMBL3633054 | 0.70 | CA12 (0.61) | HPGDRAB9ASMN1; SMN2TSHRTRPA1 | |
| SCHEMBL29551674 | 0.70 | CA12 (0.61) | HPGDRAB9ASMN1; SMN2TSHRTRPA1 | |
| SCHEMBL19577765 | 0.69 | HTR7 (0.60) | HPGDRAB9ASMN1; SMN2TSHRTRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106083686-B | The method of alpha-brominated acetophenone oxime ether synthesis 2,4- diaryl pyrrole class compound | 苏州大学 | 2019-01-22 | — | — | CN | disclosed |
| CN-106083686-A | The method that α bromoacetophenone oxime ether synthesizes 2,4 diaryl pyrrole compounds | 苏州大学 | 2016-11-09 | — | — | CN | disclosed |