Sugi Predict

Sugi Predict / Compounds / SCHEMBL17280164

SCHEMBL17280164

SCHEMBL17280164

Cc1cccc(-c2cc(-c3cccc(-c4c[nH]c(-c5cccc(C)c5C)c4)c3)c[nH]2)c1C

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ NUDT1 P36639 4/20 0.35
▸ BRD4 O60885 2/20 0.33
▸ HTR7 P34969 3/20 0.32
▸ HTR1A P08908 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.32
▸ HTT P42858 1/20 0.32
▸ TRPA1 O75762 1/20 0.31
▸ ATM Q13315 1/20 0.31
▸ KDM4E B2RXH2 1/20 0.31
▸ PTPN1 P18031 1/20 0.31
▸ FFAR1 O14842 1/20 0.30
▸ PIK3CD O00329 1/20 0.30
▸ PIK3CA P42336 1/20 0.30
▸ PIK3CB P42338 1/20 0.30
▸ PIK3CG P48736 1/20 0.30
▸ PRKDC P78527 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17280167 0.79 HSD17B1 (0.33) HTR7ALDH1A1KDM4E
SCHEMBL28113839 0.74 HPGD (0.40) BRD4HTR7HTR1ATRPA1
SCHEMBL17279892 0.73 ALOX15 (0.51) HTTKDM4E
SCHEMBL20382742 0.73 IDO1 (0.43) —
SCHEMBL27902078 0.72 CD274 (0.46) NUDT1HTR7HTR1AALDH1A1HTT
SCHEMBL31547319 0.71 BRD4 (0.41) BRD4HTR7HTR1AALDH1A1TRPA1
SCHEMBL17279776 0.71 ALDH1A1 (0.47) ALDH1A1
SCHEMBL17280200 0.70 NPC1 (0.39) ALDH1A1
SCHEMBL17280182 0.70 AURKA (0.46) ALDH1A1KDM4E
SCHEMBL6285311 0.68 AURKA (0.42) NUDT1ALDH1A1HTTTRPA1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180203175-A1 TRIAZOLE COMPOUND Konica Minolta, Inc. (JP) 2018-07-19 — — US disclosed
US-20180203175-A1 TRIAZOLE COMPOUND Konica Minolta, Inc. (JP) 2018-07-19 — — US disclosed
US-10012777-B2 Resin composition Konica Minolta, Inc. (JP) 2018-07-03 — — US disclosed
US-10012777-B2 Resin composition Konica Minolta, Inc. (JP) 2018-07-03 — — US disclosed
US-20150338563-A1 RESIN COMPOSITION, TRIAZOLE COMPOUND, OPTICAL FILM, POLARIZING PLATE, OPTICAL LENS, CIRCULARLY POLARIZING PLATE AND IMAGE DISPLAY DEVICE KONICA MINOLTA, INC (JP) 2015-11-26 — — US disclosed
US-20150338563-A1 RESIN COMPOSITION, TRIAZOLE COMPOUND, OPTICAL FILM, POLARIZING PLATE, OPTICAL LENS, CIRCULARLY POLARIZING PLATE AND IMAGE DISPLAY DEVICE KONICA MINOLTA, INC (JP) 2015-11-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150338563-A1 RESIN COMPOSITION, TRIAZOLE COMPOUND, OPTICAL FILM, POLARIZING PLATE, OPTICAL LENS, CIRCULARLY POLARIZING PLATE AND IMAGE DISPLAY DEVICE HRH3, HELZ, NBAS NUDT1 2133/4885BRD4 691/4885HTR7 257/4885
US-10012777-B2 Resin composition NBAS, WDR5, HRH3 NUDT1 1906/4885BRD4 526/4885HTR7 357/4885
US-20180203175-A1 TRIAZOLE COMPOUND H1-10, TTI2, H1-2 NUDT1 2484/4885BRD4 36/4885HTR7 1441/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.