Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | TPMT | P51580 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9928852 | 0.82 | ABCB11 (0.37) | ALDH1A1KDM4EGAAHPGDTPMT | |
| SCHEMBL9928867 | 0.74 | L3MBTL1 (0.45) | HMGCRL3MBTL1ALDH1A1KDM4EGAA | |
| SCHEMBL1262272 | 0.72 | PDE4D (0.43) | HMGCRL3MBTL1ALDH1A1KDM4EGAA | |
| SCHEMBL28114021 | 0.72 | LMNA (0.38) | HMGCRALDH1A1KDM4EGAAHPGD | |
| SCHEMBL10994734 | 0.71 | KDM4E (0.54) | HMGCRL3MBTL1ALDH1A1KDM4EHPGD | |
| SCHEMBL9720581 | 0.71 | ALDH1A1 (0.49) | HMGCRL3MBTL1ALDH1A1KDM4EGAA | |
| SCHEMBL8895935 | 0.70 | HMGCR (0.54) | HMGCRALDH1A1GAA | |
| SCHEMBL10994738 | 0.70 | KDM4E (0.44) | HMGCRL3MBTL1ALDH1A1KDM4EGAA | |
| SCHEMBL28113489 | 0.70 | LMNA (0.39) | HMGCRL3MBTL1ALDH1A1KDM4EGAA | |
| SCHEMBL12813097 | 0.69 | CYP1A2 (0.35) | ALDH1A1KDM4EGAATPMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104024253-B | Heterocyclic amines as PI3K inhibitors | INCYTE HOLDINGS CORP. (US) | 2016-11-30 | — | — | CN | disclosed |