Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28114173 | 0.74 | HTR1B (0.46) | — | |
| SCHEMBL28114576 | 0.73 | AVPR2 (0.52) | DRD2DRD3ALDH1A1L3MBTL1AVPR2 | |
| SCHEMBL28114161 | 0.71 | ALDH1A1 (0.51) | HRH3CYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL9319475 | 0.69 | HTR1A (0.62) | CYP2C19DRD2DRD3 | |
| SCHEMBL9319232 | 0.65 | HTR1A (0.61) | CYP2C19DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL7532089 | 0.65 | CYP1A2 (0.42) | SMN1; SMN2CYP1A2CYP2C9CYP2C19DRD2 | |
| SCHEMBL8780407 | 0.64 | HTR1A (0.59) | CYP2C19DRD2DRD3 | |
| Morpholine SCHEMBL21359321 | 0.63 | KDM4E (0.50) | SMN1; SMN2ALDH1A1L3MBTL1 | |
| Morpholine SCHEMBL11044062 | 0.62 | CYP1A2 (0.45) | SMN1; SMN2HRH3CYP1A2CYP2C9CYP2C19 | |
| Nitrogen SCHEMBL6142719 | 0.62 | DRD2 (0.53) | SMN1; SMN2DRD2DRD3PIK3CBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106146404-A | Pyridazinone derivative and application thereof | 江苏恩华药业股份有限公司 | 2016-11-23 | — | — | CN | disclosed |