Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 2/20 | 0.65 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.65 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.65 |
| ▸ | HTR1A | P08908 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | AVPR2 | P30518 | 5/20 | 0.58 |
| ▸ | AVPR1A | P37288 | 5/20 | 0.58 |
| ▸ | DRD2 | P14416 | 1/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8720336 | 0.86 | ALDH1A1 (0.72) | ADRA1AHTR1AKDM4EALDH1A1TDP1 | |
| SCHEMBL8724501 | 0.86 | ALDH1A1 (0.72) | ADRA1AHTR1AKDM4EALDH1A1TDP1 | |
| SCHEMBL8719445 | 0.86 | ALDH1A1 (0.72) | ADRA1AHTR1AKDM4EALDH1A1TDP1 | |
| SCHEMBL8719681 | 0.86 | ALDH1A1 (0.72) | ADRA1AHTR1AKDM4EALDH1A1TDP1 | |
| SCHEMBL8722383 | 0.85 | HTR1A (0.58) | ADRA1DADRA1AADRA1BHTR1AKDM4E | |
| SCHEMBL8719441 | 0.82 | HTR1A (0.64) | ADRA1AHTR1AKDM4EALDH1A1TDP1 | |
| SCHEMBL8719497 | 0.82 | HTR1A (0.64) | ADRA1AHTR1AKDM4EALDH1A1TDP1 | |
| SCHEMBL8724727 | 0.81 | ADRA1D (0.55) | ADRA1DADRA1AADRA1BKDM4EALDH1A1 | |
| SCHEMBL8720703 | 0.81 | ADRA1D (0.55) | ADRA1DADRA1AADRA1BKDM4EALDH1A1 | |
| SCHEMBL29135260 | 0.80 | DRD2 (0.52) | ADRA1DADRA1AADRA1BHTR1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998042692-A1 | PIPERAZINES DERIVED FROM CYCLIC AMINES, PREPARATION AND APPLICATION THEREOF AS MEDICINES | PIERRE FABRE MEDICAMENT (FR) | 1998-10-01 | — | — | WO | disclosed |