Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | TACR1 | P25103 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 2/20 | 0.37 |
| ▸ | CTSS | P25774 | 2/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28029905 | 0.80 | SMN1; SMN2 (0.38) | OPRM1TACR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28313657 | 0.78 | OPRM1 (0.41) | OPRM1TACR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27748184 | 0.78 | TACR1 (0.52) | OPRM1TACR1SLC6A4 | |
| SCHEMBL19157213 | 0.77 | TACR1 (0.45) | OPRM1TACR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28000343 | 0.76 | SMN1; SMN2 (0.33) | OPRM1PRKCA | |
| SCHEMBL7498000 | 0.74 | TSHR (0.49) | OPRM1TACR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27598326 | 0.74 | CHRNA7 (0.37) | — | |
| Tert-Butyl Formate SCHEMBL28114746 | 0.73 | MEN1 (0.42) | OPRM1NPC1LMNA | |
| SCHEMBL4522027 | 0.73 | SYK (0.46) | SLC6A2SLC6A4SLC6A3CTSLCTSS | |
| SCHEMBL28114836 | 0.72 | PRKCA (0.32) | PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106488915-A | Cyclopropylamine as LSD1 inhibitor | 因赛特公司 | 2017-03-08 | — | — | CN | disclosed |
| CN-106164066-A | Cyclopropylamines as lsd1 inhibitors | 因赛特公司 | 2016-11-23 | — | — | CN | disclosed |