Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28114857 | 0.81 | MYC (0.51) | KMT2AGLAHSP90AA1HSP90AB1HPGD | |
| SCHEMBL28115356 | 0.78 | CNR2 (0.45) | KMT2AGLAHPGDCNR2PKM | |
| SCHEMBL28114945 | 0.73 | HRH3 (0.50) | KMT2AGLAHSP90AA1HSP90AB1HPGD | |
| SCHEMBL20594105 | 0.71 | PDE4B (0.54) | HPGDCNR2L3MBTL1TSHR | |
| SCHEMBL20594128 | 0.71 | ABL1 (0.48) | HPGDRAB9A | |
| SCHEMBL31428978 | 0.70 | ALDH1A1 (0.58) | KMT2AGLAHSP90AA1HSP90AB1HPGD | |
| SCHEMBL20594991 | 0.68 | TGFBR1 (0.39) | KMT2AHSP90AA1HSP90AB1HPGD | |
| SCHEMBL9173237 | 0.65 | KMT2A (0.77) | KMT2AGLAHPGDL3MBTL1MAPK1 | |
| SCHEMBL10720509 | 0.65 | L3MBTL1 (0.71) | KMT2AHPGDPKML3MBTL1MAPK1 | |
| SCHEMBL15713725 | 0.65 | KMT2A (0.67) | KMT2AHSP90AA1HSP90AB1HPGDCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106243012-A | New indole analog derivative and preparation method thereof | 北方民族大学 | 2016-12-21 | — | — | CN | disclosed |