Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28114857 | 0.84 | MYC (0.51) | CNR2KMT2ALMNAHPGDCNR1 | |
| SCHEMBL28114905 | 0.78 | KMT2A (0.45) | CNR2KMT2AHPGDCNR1RAB9A | |
| SCHEMBL28837064 | 0.76 | L3MBTL1 (0.51) | CNR2ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL20594128 | 0.68 | ABL1 (0.48) | ALDH1A1HPGDRAB9A | |
| SCHEMBL20594105 | 0.68 | PDE4B (0.54) | CNR2HPGD | |
| SCHEMBL28115352 | 0.67 | JAK2 (0.56) | CNR2ALDH1A1KMT2AMEN1HSD17B10 | |
| SCHEMBL20306406 | 0.65 | HSD17B10 (0.66) | ALDH1A1KMT2AHSD17B10LMNAHPGD | |
| SCHEMBL20594991 | 0.65 | TGFBR1 (0.39) | KMT2AHPGD | |
| SCHEMBL15650909 | 0.64 | HSD17B10 (0.65) | ALDH1A1KMT2AHSD17B10LMNAHPGD | |
| SCHEMBL2219985 | 0.64 | HRH3 (0.83) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106243012-A | New indole analog derivative and preparation method thereof | 北方民族大学 | 2016-12-21 | — | — | CN | disclosed |