Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28115356 | 0.84 | CNR2 (0.45) | HPGDCNR2PKMKMT2ACNR1 | |
| SCHEMBL28114905 | 0.81 | KMT2A (0.45) | HPGDCNR2PKMHSP90AA1HSP90AB1 | |
| SCHEMBL20594128 | 0.74 | ABL1 (0.48) | HPGD | |
| SCHEMBL20594105 | 0.74 | PDE4B (0.54) | HPGDCNR2L3MBTL1TSHR | |
| SCHEMBL15556917 | 0.72 | HTR3A (0.57) | HPGDKMT2A | |
| SCHEMBL6674814 | 0.72 | AKR1C3 (0.62) | KMT2ALMNA | |
| SCHEMBL28114852 | 0.71 | L3MBTL1 (0.56) | MYCCNR2L3MBTL1KMT2ARECQL | |
| SCHEMBL20594991 | 0.71 | TGFBR1 (0.39) | HPGDHSP90AA1HSP90AB1KMT2A | |
| SCHEMBL17559459 | 0.70 | MYC (0.62) | MYCHPGDPKMHSP90AA1HSP90AB1 | |
| SCHEMBL17479132 | 0.70 | MYC (0.59) | MYCHPGDPKMHSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106243012-A | New indole analog derivative and preparation method thereof | 北方民族大学 | 2016-12-21 | — | — | CN | disclosed |