Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 9/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | PRNP | P04156 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28115569 | 0.88 | KDM4E (0.50) | DHODHKMT2AMAPTHPGDALDH1A1 | |
| SCHEMBL28837021 | 0.87 | MAPT (0.60) | DHODHMEN1KMT2AMAPTHPGD | |
| SCHEMBL28115477 | 0.86 | RXFP1 (0.52) | MEN1KMT2AMAPTHPGDPOLB | |
| SCHEMBL28115022 | 0.86 | DHODH (0.53) | DHODHMAPTPLA2G2AHPGDALDH1A1 | |
| SCHEMBL28837077 | 0.86 | TRPV1 (0.43) | DHODHMEN1KMT2AMAPTHPGD | |
| Hydrochloric Acid SCHEMBL26649609 | 0.84 | DHODH (0.57) | DHODHMEN1KMT2APLA2G2AHPGD | |
| SCHEMBL28115083 | 0.84 | MAPT (0.48) | DHODHMAPTPLA2G2AHPGDALDH1A1 | |
| SCHEMBL30747799 | 0.81 | DHODH (0.54) | DHODHMEN1KMT2APLA2G2AALDH1A1 | |
| SCHEMBL26649377 | 0.81 | DHODH (0.54) | DHODHMEN1KMT2APLA2G2AALDH1A1 | |
| SCHEMBL28115474 | 0.81 | MAPT (0.60) | MEN1KMT2AMAPTHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106220560-A | A kind of preparation method of poly-substituted quinoline derivant | 华侨大学 | 2016-12-14 | — | — | CN | disclosed |